| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4809906 | ADME | Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assay | Homo sapiens | 43 | ALA4808200 | single protein format | Scientific Literature | |
| 2. | ALA4809907 | Binding | Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assay | Homo sapiens | 43 | ALA4808200 | single protein format | Scientific Literature | |
| 3. | ALA4809908 | Binding | Selectivity index, ratio of IC50 for displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD1 (1 to 477 residue)/BD2 Y390A mutant (unknown origin) to IC50 for displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2 (1 to 477 residue)/BD1 Y97A mutant (unknown origin) | Homo sapiens | 42 | ALA4808200 | assay format | Scientific Literature | |
| 4. | ALA4809909 | Physicochemical | Chromatographic hydrophobicity index, log D of the compound at pH 7.4 by HPLC analysis | 42 | ALA4808200 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4809911 | ADME | Permeability of the compound at pH 7.4 by artificial membrane permeability assay | 42 | ALA4808200 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!