# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA634125 | A | plasma concentration at the 2.5 hour time | 2 | ALA1135599 | cell-free format | Scientific Literature | ||
2. | ALA636279 | A | Area under curve (AUC) value in dogs after an intravenous dose of 0.2 mg/Kg in 0.025 M aqueous methanesulfonic acid solution with 5% mannitol | 2 | ALA1135599 | assay format | Scientific Literature | ||
3. | ALA646698 | A | Plasma clearance in dogs after an intravenous dose of 0.2 mg/Kg | Canis lupus familiaris | 3 | ALA1135599 | organism-based format | Scientific Literature | |
4. | ALA643190 | A | Volume distribution in dogs after an intravenous dose of 0.2 mg/Kg | 3 | ALA1135599 | organism-based format | Scientific Literature | ||
5. | ALA639885 | A | Half life (t1/2) value in dogs after an intravenous dose of 0.2 mg/Kg | Canis lupus familiaris | 4 | ALA1135599 | organism-based format | Scientific Literature | |
6. | ALA647214 | B | Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human receptor in the presence of [125I]iodocyanopindolol | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
7. | ALA652427 | B | Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human receptor in the presence of [125I]iodocyanopindolol | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
8. | ALA654936 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoproterenol (ISO).Emax is the fitted maximal value of the concentration | 3 | ALA1135599 | assay format | Scientific Literature | ||
9. | ALA654937 | F | Concentration that causes 50% inhibition of human beta 1 adrenergic receptor (AR), expressed in CHO cells. | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
10. | ALA654953 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoproterenol (ISO).Emax is the fitted maximal value of the concentration | 3 | ALA1135599 | assay format | Scientific Literature | ||
11. | ALA858099 | F | Concentration that causes 50% inhibition of human beta 2 adrenergic receptor (AR), expressed in CHO cells. | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
12. | ALA654145 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoproterenol (ISO).Emax is the fitted maximal value of the concentration | 16 | ALA1135599 | assay format | Scientific Literature | ||
13. | ALA654147 | F | Ability to cause cAMP accumulation in CHO cells expressing human beta-3 AR expressed as the negative logarithm of the molar drug concentration | 13 | ALA1135599 | cell-based format | Scientific Literature | ||
14. | ALA847414 | F | Selectivity ratio (Beta-1EC50/ Beta-3EC50) | 18 | ALA1135599 | assay format | Scientific Literature | ||
15. | ALA880372 | F | Selectivity ratio (Beta-2EC50/ Beta-3EC50) | 19 | ALA1135599 | assay format | Scientific Literature | ||
16. | ALA862145 | F | Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
17. | ALA862146 | F | Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
18. | ALA862147 | F | Selectivity for human beta3 adrenergic receptor over beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
19. | ALA862149 | F | Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
20. | ALA862150 | F | Selectivity for human beta-3 adrenergic receptor over beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature |