# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4834035 | Binding | Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay | Homo sapiens | 50 | ALA4831554 | cell-based format | Scientific Literature | |
2. | ALA4834036 | Physicochemical | Lipophilicity, logD of the compound in Octanol/phosphate buffer at pH 7.4 after 30 mins by shake-flask method | 50 | ALA4831554 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4834037 | ADME | Intrinsic clearance in human liver microsomes at 1 uM preincubated with NADPH for 5 mins followed by compound addition and measured upto 30 mins by LC-MS/MS analysis | Homo sapiens | 50 | ALA4831554 | microsome format | Scientific Literature | |
4. | ALA4834038 | Physicochemical | Solubility of compound in phosphate buffer at pH 7.4 measured after 24 hrs by LC-MS/MS analysis | 50 | ALA4831554 | small-molecule physicochemical format | Scientific Literature |