#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4835172	Binding	Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay	Homo sapiens	60	ALA4834410	single protein format	Scientific Literature
2.	ALA4835174	Binding	Inhibition of human recombinant ADAMTS-1 (AA253 to 734) assessed as cleavage of fluorescent substrate using 5(6)-fluorescein-NH-AELQGRPISIAK-5(6)-TAMRA as substrate incubated for 120 mins by biochemical assay	Homo sapiens	15	ALA4834410	single protein format	Scientific Literature
3.	ALA4835175	Binding	Inhibition of human recombinant ADAMTS-4 (AA1 to 520) assessed as cleavage of fluorescent substrate using as TBIS-1 substrate incubated for 180 mins by biochemical assay	Homo sapiens	14	ALA4834410	single protein format	Scientific Literature
4.	ALA4835176	Binding	Inhibition of human recombinant MMP2 (AA34 to 660) assessed as cleavage of fluorescent substrate using 390 MMP FRET as substrate incubated for 30 mins by biochemical assay	Homo sapiens	14	ALA4834410	single protein format	Scientific Literature
5.	ALA4835178	Binding	Inhibition of human recombinant TACE (AA34 to 660) assessed as cleavage of fluorescent substrate using 5FAM-LAQAVRSSSRK-5TAMRA as substrate by biochemical assay	Homo sapiens	14	ALA4834410	single protein format	Scientific Literature
6.	ALA4835204	ADME	AUC in Sprague-Dawley rat at 5 mg/kg, po	Rattus norvegicus	5	ALA4834410	organism-based format	Scientific Literature
7.	ALA4835205	ADME	Cmax in Sprague-Dawley rat at 5 mg/kg, po	Rattus norvegicus	5	ALA4834410	organism-based format	Scientific Literature
8.	ALA4835206	Binding	Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in absence of serum by biochemical assay	Homo sapiens	3	ALA4834410	single protein format	Scientific Literature
9.	ALA4835207	Binding	Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in presence of 2% HSA by biochemical assay	Homo sapiens	3	ALA4834410	single protein format	Scientific Literature
10.	ALA4835208	Binding	Ratio of IC50 for human recombinant ADAMTS-5 in presence of 2% HSA to human recombinant ADAMTS-5 in absence of serum	Homo sapiens	3	ALA4834410	assay format	Scientific Literature
11.	ALA4835209	ADME	Plasma protein binding in human at 5 uM measured after 4 hrs by LC-MS/MS analysis	Homo sapiens	6	ALA4834410	cell-free format	Scientific Literature