# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4843536 | Binding | Inhibition of Candida albicans CYP51 assessed as lanosterol level at 0.015 ug/ml measured after 18 hrs by GC-MS analysis relative to control | Candida albicans | 2 | ALA4842346 | single protein format | Scientific Literature | |
2. | ALA4843537 | Functional | Antifungal activity against Candida tropicalis GIM2.183 assessed as inhibition of fungal growth by NCCLS protocol based method | Candida tropicalis | 35 | ALA4842346 | organism-based format | Scientific Literature | |
3. | ALA4843539 | Functional | Antifungal activity against Candida albicans SC5314 assessed as inhibition of fungal growth by NCCLS protocol based method | Candida albicans | 43 | ALA4842346 | organism-based format | Scientific Literature | |
4. | ALA4843542 | Functional | Antifungal activity against Aspergillus fumigatus CGMCC3.7795 assessed as inhibition of fungal growth by NCCLS protocol based method | Aspergillus fumigatus | 43 | ALA4842346 | organism-based format | Scientific Literature | |
5. | ALA4843543 | Functional | Antifungal activity against Candida albicans GIM2.194 assessed as inhibition of fungal growth by NCCLS protocol based method | Candida albicans | 35 | ALA4842346 | organism-based format | Scientific Literature | |
6. | ALA4843544 | Functional | Antifungal activity against Candida krusei GIM2.1 assessed as inhibition of fungal growth by NCCLS protocol based method | Pichia kudriavzevii | 27 | ALA4842346 | organism-based format | Scientific Literature | |
7. | ALA4843545 | Functional | Antifungal activity against Candida parapsilosis GIM2.190 assessed as inhibition of fungal growth by NCCLS protocol based method | Candida parapsilosis | 27 | ALA4842346 | organism-based format | Scientific Literature | |
8. | ALA4843546 | Functional | Antifungal activity against fluconazole resistant Candida albicans CaR assessed as inhibition of fungal growth by NCCLS protocol based method | Candida albicans | 9 | ALA4842346 | organism-based format | Scientific Literature | |
9. | ALA4843547 | Functional | Antifungal activity against fluconazole and itraconazole resistant Candida albicans 17# assessed as inhibition of fungal growth by NCCLS protocol based method | Candida albicans | 9 | ALA4842346 | organism-based format | Scientific Literature | |
10. | ALA4843548 | ADME | Metabolic stability in human liver microsomes assessed as half life at 100 uM in the presence of NADPH measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 5 | ALA4842346 | microsome format | Scientific Literature | |
11. | ALA4843549 | ADME | Intrinsic microsomal clearance in human liver microsomes at 100 uM in the presence of NADPH measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
12. | ALA4843550 | ADME | Intrinsic hepatic clearance in human liver microsomes at 100 uM in the presence of NADPH measured up to 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
13. | ALA4843551 | ADME | Metabolic stability in human liver microsomes assessed as compound remaining at 100 uM measured after 60 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
14. | ALA4843552 | ADME | Metabolic stability in human liver microsomes assessed as compound remaining at 100 uM measured after 60 mins in the absence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
15. | ALA4843553 | ADME | Metabolic stability in human plasma assessed as parent compound remaining at 100 uM measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | cell-free format | Scientific Literature | |
16. | ALA4843554 | ADME | Metabolic stability in human plasma assessed as parent compound remaining at 100 uM measured after 120 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | cell-free format | Scientific Literature | |
17. | ALA4843555 | ADME | Metabolic stability in human plasma assessed as half life at 100 uM measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | cell-free format | Scientific Literature | |
18. | ALA4843556 | ADME | Inhibition of CYP1A2 in human liver microsome incubated for 10 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
19. | ALA4843557 | ADME | Inhibition of CYP2C9 in human liver microsome incubated for 10 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature | |
20. | ALA4843558 | ADME | Inhibition of CYP2C19 in human liver microsome incubated for 10 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4842346 | microsome format | Scientific Literature |