#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4831635	B	Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and measured after 1 hr by fluorescent polarization assay	Homo sapiens	23		assay format	Scientific Literature
2.	ALA4831636	B	Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and measured after 1 hr by fluorescent polarization assay	Homo sapiens	16		assay format	Scientific Literature
3.	ALA4831637	B	Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and measured after 1 hr by fluorescent polarization assay	Homo sapiens	16		assay format	Scientific Literature
4.	ALA4831638	B	Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and measured after 1 hr by fluorescent polarization assay	Homo sapiens	16		assay format	Scientific Literature
5.	ALA4831639	F	Antiproliferative activity against human MCF7 cells assessed as growth inhibition preincubated with estradiol for 30 mins followed by compound addition and measured after 72 hrs by CellTiter-Glo assay	Homo sapiens	23		cell-based format	Scientific Literature
6.	ALA4831640	F	Antiproliferative activity against human MCF7 cells assessed as growth inhibition preincubated with estradiol for 30 mins followed by compound addition and measured after 7 days by CellTiter-Glo assay	Homo sapiens	23		cell-based format	Scientific Literature
7.	ALA4831643	B	Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein expression incubated for 48 hrs by Western blot analysis	Homo sapiens	9		cell-based format	Scientific Literature
8.	ALA4831659	P	Solubility of compound		4		small-molecule physicochemical format	Scientific Literature
9.	ALA4831660	A	Apparent permeability of compound across apical to basolateral side in MDCK cells	Canis lupus familiaris	4		cell-based format	Scientific Literature
10.	ALA4831661	A	Plasma protein binding in human	Homo sapiens	4		cell-free format	Scientific Literature
11.	ALA4831662	A	Microsomal stability in human liver microsomes assessed as intrinsic clearance measured upto 60 mins	Homo sapiens	4		microsome format	Scientific Literature
12.	ALA4831663	A	Microsomal stability in mouse liver microsomes assessed as intrinsic clearance measured upto 60 mins	Mus musculus	4		microsome format	Scientific Literature
13.	ALA4831664	A	Clearance in CD1 mouse at 0.3 mg/kg, iv administered as cassette dosing measured upto 24 hrs	Mus musculus	4		organism-based format	Scientific Literature
14.	ALA4831665	A	Volume of distribution at steady state in CD1 mouse at 0.3 mg/kg, iv administered as cassette dosing measured upto 24 hrs	Mus musculus	4		organism-based format	Scientific Literature
15.	ALA4831666	A	Half life in CD1 mouse at 0.3 mg/kg, iv administered as cassette dosing measured upto 24 hrs	Mus musculus	4		organism-based format	Scientific Literature
16.	ALA4831667	A	Cmax in CD1 mouse at 10 mg/kg, sc administered as single dose measured upto 8 hrs	Mus musculus	4		organism-based format	Scientific Literature
17.	ALA4831668	A	AUCinfinity in CD1 mouse at 10 mg/kg, sc administered as single dose measured upto 8 hrs	Mus musculus	4		organism-based format	Scientific Literature
18.	ALA4831669	A	Half life in CD1 mouse at 10 mg/kg, sc administered as single dose measured upto 8 hrs	Mus musculus	4		organism-based format	Scientific Literature
19.	ALA4831670	A	Bioavailability in CD1 mouse at 10 mg/kg, sc administered as single dose measured upto 8 hrs	Mus musculus	4		organism-based format	Scientific Literature