| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4834258 | F | Antiproliferative activity against mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferation assay | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4834259 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferation assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA4834294 | B | Inhibition of Tel fused KDR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferation assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 4. | ALA4834295 | B | Inhibition of RET (658 to 1072) (unknown origin) by HTRF assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 5. | ALA4834297 | A | Clearance in BALB/c mouse at 2 mg/kg, iv measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4834299 | A | Volume of distribution at steady state in BALB/c mouse at 2 mg/kg, iv measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4834302 | A | Half life in BALB/c mouse at 2 mg/kg, iv measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4834303 | A | Half life in BALB/c mouse at 10 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4834306 | A | AUC in BALB/c mouse at 2 mg/kg, iv measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA4834307 | A | AUC in BALB/c mouse at 10 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA4834310 | A | Cmax in BALB/c mouse at 2 mg/kg, iv measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA4834311 | A | Cmax in BALB/c mouse at 10 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA4834313 | A | Oral bioavailability in BALB/c mouse at 10 mg/kg measured by LC-MS/MS analysis | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA4834314 | A | Ratio of AUC in BALB/c mouse brain to plasma at 10 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA4834315 | A | Ratio of Cmax in BALB/c mouse brain to plasma at 10 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 16. | ALA4834316 | B | Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in human LC-2-ad cells assessed as reduction in cell proliferation incubated for 6 days by d CellTiter Glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4834317 | B | Displacement of [3H]-dofetilide from human ERG expressed in CHO cell after 90 mins by microbeta liquid scintillation counting method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4834318 | B | Inhibition of human ERG expressed in CHO cells by manual patch clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4834319 | A | Plasma protein binding in mouse at 5 uM measured after 16 hrs by LC-MS/MS based rapid equilibrium dialysis analysis | Mus musculus | 4 | cell-free format | Scientific Literature | ||
| 20. | ALA4834320 | A | AUC in nude mouse xenografted with KIF5B-RET BaF3 cells xenografted at 60 mg/kg, po qd for 14 days | Mus musculus | 1 | organism-based format | Scientific Literature |
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