# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4827730 | B | Inhibition of NF-kappaB in human U-937 cells assessed as reduction in translocation of p65 NF-kappaB in from cytosol to nucleus at 0.01 uM treated followed by 3 hrs LPS stimulation by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
2. | ALA4827731 | B | Inhibition of NF-kappaB in human U-937 cells assessed as reduction in translocation of p65 NF-kappaB in from cytosol to nucleus at 0.01 uM treated followed by 3 hrs LPS stimulation hrs by immunohistochemical staining/confocal microscopy | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA4827732 | F | Anti-inflammatory activity in human U-937 cells assessed as reduction in LPS-induced ROS production at 0.01 uM followed by LPS stimulation and measured after 24 hrs relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4827733 | F | Anti-inflammatory activity in human U-937 cells assessed as reduction in LPS-induced NO production at 0.01 uM followed by LPS stimulation and measured after 24 hrs relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4827734 | B | Inhibition of NF-kappaB activation in human U-937 cells assessed as reduction in LPS-induced ACLY activity after 48 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4827735 | B | Inhibition of NF-kappaB activation in human U-937 cells assessed as reduction in LPS-induced PGE2 production after 48 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4827737 | B | Inhibition of NF-kappaB in human U-937 cells assessed as reduction in LPS-induced p65 expression at 0.01 uM treated followed by 3 hrs LPS stimulation by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature |