# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4838702 | Binding | Inhibition of MERTK (unknown origin) | Homo sapiens | 35 | ALA4837224 | single protein format | Scientific Literature | |
2. | ALA4838703 | Binding | Inhibition of AXL (unknown origin) | Homo sapiens | 35 | ALA4837224 | single protein format | Scientific Literature | |
3. | ALA4838704 | Binding | Inhibition of TYRO3 (unknown origin) | Homo sapiens | 35 | ALA4837224 | single protein format | Scientific Literature | |
4. | ALA4838705 | Binding | Inhibition of FLT3 (unknown origin) | Homo sapiens | 35 | ALA4837224 | single protein format | Scientific Literature | |
5. | ALA4838706 | Binding | Selectivity index, ratio of IC50 for inhibition of FLT3 (unknown origin) to IC50 for inhibition of MERTK (unknown origin) | Homo sapiens | 35 | ALA4837224 | assay format | Scientific Literature | |
6. | ALA4838709 | Binding | Inhibition of N-terminal GST-tagged AXL (464 to 885 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature | |
7. | ALA4838710 | ADME | Half life in mouse at 3 mg/kg, iv | Mus musculus | 7 | ALA4837224 | organism-based format | Scientific Literature | |
8. | ALA4838711 | ADME | Cmax in mouse at 3 mg/kg, iv | Mus musculus | 7 | ALA4837224 | organism-based format | Scientific Literature | |
9. | ALA4838712 | ADME | AUClast in mouse at 3 mg/kg, iv | Mus musculus | 7 | ALA4837224 | organism-based format | Scientific Literature | |
10. | ALA4838713 | ADME | Volume of distribution at steady state in mouse at 3 mg/kg, iv | Mus musculus | 7 | ALA4837224 | organism-based format | Scientific Literature | |
11. | ALA4838714 | ADME | Clearance in mouse at 3 mg/kg, iv | Mus musculus | 7 | ALA4837224 | organism-based format | Scientific Literature | |
12. | ALA4838715 | ADME | Inhibition of CYP2D6 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA4837224 | single protein format | Scientific Literature | |
13. | ALA4838716 | ADME | Inhibition of CYP2C9 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA4837224 | single protein format | Scientific Literature | |
14. | ALA4838717 | ADME | Inhibition of CYP2C19 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA4837224 | single protein format | Scientific Literature | |
15. | ALA4838719 | ADME | Inhibition of CYP1A2 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4837224 | single protein format | Scientific Literature | |
16. | ALA4838720 | Binding | Inhibition of N-terminal GST-tagged MERTK (528 to 999 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature | |
17. | ALA4838721 | Binding | Inhibition of N-terminal GST-tagged FLT3 (564 to 993 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature | |
18. | ALA4838722 | Binding | Inhibition of N-terminal GST-tagged TYRO3 (453 to 890 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature | |
19. | ALA4838723 | Binding | Inhibition of N-terminal GST-tagged TRKA (436 to 790 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature | |
20. | ALA4838724 | Binding | Inhibition of N-terminal GST-tagged TRKC (456 to 825 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cells | Homo sapiens | 2 | ALA4837224 | cell-based format | Scientific Literature |