# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4844381 | A | Half life in ICR mouse at 3 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis | Mus musculus | 5 | organism-based format | Scientific Literature | ||
2. | ALA4844382 | A | Tmax in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis | Mus musculus | 5 | organism-based format | Scientific Literature | ||
3. | ALA4844383 | A | Half life in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis | Mus musculus | 5 | organism-based format | Scientific Literature | ||
4. | ALA4844384 | B | Protac activity at VHL3/AR in human VCaP cells assessed as induction of AR degradation at 0.001 uM measured after 24 hrs by western blot analysis relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
5. | ALA4844385 | B | Protac activity at VHL3/AR in human VCaP cells assessed as induction of AR degradation at 0.01 uM measured after 24 hrs by western blot analysis relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
6. | ALA4844386 | B | Protac activity at VHL3/AR in human VCaP cells assessed as induction of AR degradation at 0.1 uM measured after 24 hrs by western blot analysis relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
7. | ALA4844387 | B | Protac activity at VHL3/AR in human VCAP cells assessed as induction of AR degradation at 1 uM by western blot analysis relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
8. | ALA4844391 | B | Protac activity at VHL/AR in human VCaP cells assessed as induction of AR degradation measured after 24 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA4844392 | B | Protac activity at VHL/AR T878A mutant in human LNCaP cells assessed as induction of AR degradation measured after 24 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4844393 | B | Protac activity at VHL/AR in human VCaP cells assessed as reduction in AR protein level at 100 nM measured after 3 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA4844394 | B | Protac activity at VHL/AR T878A mutant in human LNCaP cells assessed as reduction in AR protein level at 100 nM measured after 6 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA4844395 | F | Growth inhibition of human VCaP cells assessed as cell viability measured after 4 days in presence of R1881 by WST-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
13. | ALA4844396 | F | Growth inhibition of human LNCaP cells assessed as cell viability measured after 4 days in presence of R1881 by WST-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
14. | ALA4844397 | B | Induction of AR degradation in human LNCaP cells at 100 nM treated for 3 hrs followed by treated with ARi-184 for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4844398 | B | Induction of AR degradation in human LNCaP cells at 100 nM treated for 3 hrs followed by treated with thalidomide for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4844399 | B | Induction of AR degradation in human LNCaP cells at 100 nM treated for 3 hrs followed by treated with MG132 for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4844400 | B | Induction of AR degradation in human LNCaP cells at 100 nM treated for 3 hrs followed by treated with MLN4924 for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4844401 | B | Induction of AR degradation in human VCaP cells at 100 nM treated for 3 hrs followed by treated with ARi-184 for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4844402 | B | Induction of AR degradation in human VCaP cells at 100 nM treated for 3 hrs followed by treated with thalidomide for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4844403 | B | Induction of AR degradation in human VCaP cells at 100 nM treated for 3 hrs followed by treated with MG132 for 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature |