# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA647214 | B | Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human receptor in the presence of [125I]iodocyanopindolol | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
2. | ALA652427 | B | Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human receptor in the presence of [125I]iodocyanopindolol | 3 | ALA1135599 | cell-based format | Scientific Literature | ||
3. | ALA654940 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoproterenol (ISO).Emax is the fitted maximal value of the concentration | 14 | ALA1135599 | assay format | Scientific Literature | ||
4. | ALA654941 | F | Ability to cause cAMP accumulation in CHO cells expressing human beta-1 AR expressed as the negative logarithm of the molar drug concentration | 14 | ALA1135599 | cell-based format | Scientific Literature | ||
5. | ALA656089 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoprenaline (ISO).Emax is the fitted maximal value of the concentration | 3 | ALA1135599 | assay format | Scientific Literature | ||
6. | ALA655820 | F | Ability to cause cAMP accumulation in CHO cells expressing human beta-2 AR expressed as the negative logarithm of the molar drug concentration | 14 | ALA1135599 | cell-based format | Scientific Literature | ||
7. | ALA654145 | F | concentration-response expressed as a percent of the maximal response to R-(-) isoproterenol (ISO).Emax is the fitted maximal value of the concentration | 16 | ALA1135599 | assay format | Scientific Literature | ||
8. | ALA654147 | F | Ability to cause cAMP accumulation in CHO cells expressing human beta-3 AR expressed as the negative logarithm of the molar drug concentration | 13 | ALA1135599 | cell-based format | Scientific Literature | ||
9. | ALA847414 | F | Selectivity ratio (Beta-1EC50/ Beta-3EC50) | 18 | ALA1135599 | assay format | Scientific Literature | ||
10. | ALA880372 | F | Selectivity ratio (Beta-2EC50/ Beta-3EC50) | 19 | ALA1135599 | assay format | Scientific Literature | ||
11. | ALA862145 | F | Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
12. | ALA862146 | F | Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
13. | ALA862147 | F | Selectivity for human beta3 adrenergic receptor over beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
14. | ALA862149 | F | Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
15. | ALA862150 | F | Selectivity for human beta-3 adrenergic receptor over beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
16. | ALA863070 | F | Activity against human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP production relative to R-(-)-isoproterenol | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
17. | ALA863073 | F | Activity against human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production relative to R-(-)-isoproterenol | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
18. | ALA863074 | F | Activity against human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production relative to R-(-)-isoproterenol | Homo sapiens | 15 | ALA1147662 | cell-based format | Scientific Literature | |
19. | ALA887284 | F | Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation | Homo sapiens | 16 | ALA1140647 | cell-based format | Scientific Literature | |
20. | ALA887285 | F | Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation | Homo sapiens | 16 | ALA1140647 | cell-based format | Scientific Literature |