# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4822448 | Binding | Inhibition of BTK (unknown origin) | Homo sapiens | 33 | ALA4819115 | single protein format | Scientific Literature | |
2. | ALA4822449 | Binding | Inhibition of BTK in human whole blood | Homo sapiens | 4 | ALA4819115 | tissue-based format | Scientific Literature | |
3. | ALA4822450 | Binding | Inhibition of BTK in human PBMC | Homo sapiens | 27 | ALA4819115 | tissue-based format | Scientific Literature | |
4. | ALA4822451 | ADME | Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells | Homo sapiens | 29 | ALA4819115 | cell-based format | Scientific Literature | |
5. | ALA4822452 | ADME | Efflux ratio of apparent permeability in human Caco-2 cells | Homo sapiens | 29 | ALA4819115 | cell-based format | Scientific Literature | |
6. | ALA4822455 | Binding | Inhibition of human ERG at 30 uM | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
7. | ALA4822456 | ADME | Fraction unbound in human | Homo sapiens | 1 | ALA4819115 | assay format | Scientific Literature | |
8. | ALA4822457 | ADME | Fraction unbound in mouse | Mus musculus | 1 | ALA4819115 | organism-based format | Scientific Literature | |
9. | ALA4822458 | ADME | Fraction unbound in rat | Rattus norvegicus | 1 | ALA4819115 | assay format | Scientific Literature | |
10. | ALA4822459 | ADME | Intrinsic clearance in human microsomes | Homo sapiens | 1 | ALA4819115 | microsome format | Scientific Literature | |
11. | ALA4822460 | ADME | Intrinsic clearance in mouse microsomes | Mus musculus | 1 | ALA4819115 | microsome format | Scientific Literature | |
12. | ALA4822461 | ADME | Intrinsic clearance in rat microsomes | Rattus norvegicus | 1 | ALA4819115 | microsome format | Scientific Literature | |
13. | ALA4822462 | ADME | Stability of the compound in human plasma assessed as parent compound remaining after 4 hrs | Homo sapiens | 1 | ALA4819115 | cell-free format | Scientific Literature | |
14. | ALA4822463 | ADME | Stability of the compound in mouse plasma assessed as parent compound remaining after 4 hrs | Mus musculus | 1 | ALA4819115 | cell-free format | Scientific Literature | |
15. | ALA4822464 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
16. | ALA4822465 | ADME | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
17. | ALA4822466 | Binding | Inhibition of human BTK at 1 uM | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
18. | ALA4822467 | Binding | Inhibition of human FGR at 1 uM | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
19. | ALA4822468 | Binding | Inhibition of human SRC at 1 uM | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature | |
20. | ALA4822469 | Binding | Inhibition of human Aurora-A at 1 uM | Homo sapiens | 1 | ALA4819115 | single protein format | Scientific Literature |