# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4810886 | B | Induction of ERalpha degradation in human MCF7 cells by immunofluorescence assay | Homo sapiens | 20 | ALA4808242 | cell-based format | Scientific Literature | |
2. | ALA4810887 | B | Induction of ERalpha degradation in human MCF7 cells assessed as maximum degradation by immunofluorescence assay relative to control | Homo sapiens | 19 | ALA4808242 | cell-based format | Scientific Literature | |
3. | ALA4810888 | F | Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability measured by CellTiter-Glo luminescent assay assay | Homo sapiens | 4 | ALA4808242 | cell-based format | Scientific Literature | |
4. | ALA4810889 | P | Distribution coefficient, logD of the compound at pH 7.4 | 20 | ALA4808242 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4810890 | A | Apparent permeability across apical to basolateral side in MDCK cells | Canis lupus familiaris | 5 | ALA4808242 | cell-based format | Scientific Literature | |
6. | ALA4810891 | A | Apparent permeability across basolateral to apical side in MDCK cells | Canis lupus familiaris | 5 | ALA4808242 | cell-based format | Scientific Literature | |
7. | ALA4810894 | P | Kinetic solubility of compound at pH 7.4 | 20 | ALA4808242 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4810897 | B | Displacement of fluorescein PGC1alpha from recombinant ERalpha (unknown origin) | Homo sapiens | 3 | ALA4808242 | single protein format | Scientific Literature | |
9. | ALA4810898 | A | Clearance in rat liver microsome | Rattus norvegicus | 4 | ALA4808242 | microsome format | Scientific Literature | |
10. | ALA4810899 | A | Clearance in rat hepatocytes | Rattus norvegicus | 4 | ALA4808242 | cell-based format | Scientific Literature | |
11. | ALA4810900 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 4 | ALA4808242 | organism-based format | Scientific Literature | |
12. | ALA4810901 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 4 | ALA4808242 | assay format | Scientific Literature | |
13. | ALA4810902 | A | Half life in rat | Rattus norvegicus | 4 | ALA4808242 | assay format | Scientific Literature | |
14. | ALA4810904 | A | Oral bioavailability in rat | Rattus norvegicus | 4 | ALA4808242 | organism-based format | Scientific Literature |