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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4812410 Binding Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintillation counter analysis Homo sapiens 32 ALA4811251 protein complex format Scientific Literature 2. ALA4812411 Functional Antiproliferative activity against human MV4-11 cells assessed as growth inhibition after 72 hrs by resazurin assay Homo sapiens 32 ALA4811251 cell-based format Scientific Literature 3. ALA4812412 Binding Inhibition of GSK3alpha (unknown origin) assessed as residual activity at 1 uM relative to control Homo sapiens 2 ALA4811251 single protein format Scientific Literature 4. ALA4812413 Binding Inhibition of GSK3beta (unknown origin) assessed as residual activity at 1 uM relative to control Homo sapiens 2 ALA4811251 single protein format Scientific Literature 5. ALA4812414 Binding Inhibition of PKC delta (unknown origin) assessed as residual activity at 1 uM relative to control Homo sapiens 2 ALA4811251 single protein format Scientific Literature 6. ALA4812415 Binding Inhibition of CDK1/Cyclin B (unknown origin) assessed as residual activity at 1 uM relative to control Homo sapiens 2 ALA4811251 protein complex format Scientific Literature 7. ALA4812416 Binding Inhibition of CDK9/Cyclin T1 (unknown origin) assessed as residual activity at 1 uM relative to control Homo sapiens 2 ALA4811251 protein complex format Scientific Literature 8. ALA4812417 ADME Volume of distribution at steady state in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 9. ALA4812418 ADME Volume of distribution at steady state in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 10. ALA4812419 ADME Clearance in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 11. ALA4812420 ADME Clearance in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 12. ALA4812421 ADME Cmax in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 13. ALA4812422 ADME Cmax in Sprague-Dawley rat at 20 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 14. ALA4812423 ADME Cmax in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 15. ALA4812424 ADME Cmax in BALB/c mouse at 10 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 16. ALA4812425 ADME Tmax in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 17. ALA4812426 ADME Tmax in Sprague-Dawley rat at 20 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature 18. ALA4812427 ADME Tmax in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 19. ALA4812428 ADME Tmax in BALB/c mouse at 10 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Mus musculus 2 ALA4811251 organism-based format Scientific Literature 20. ALA4812429 ADME Half life in Sprague-Dawley rat at 5 mg/kg, iv measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 2 ALA4811251 organism-based format Scientific Literature