# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4822364 | Binding | Activation of PKM2 (unknown origin) by pyruvate kinase-lactate dehydrogenase coupled assay | Homo sapiens | 4 | ALA4819109 | single protein format | Scientific Literature | |
2. | ALA4822365 | Functional | Growth inhibition of human Colo-201 cells by MTT assay | Homo sapiens | 5 | ALA4819109 | cell-based format | Scientific Literature | |
3. | ALA4822366 | Functional | Growth inhibition of human BCL2 Jurkat cells by MTT assay | Homo sapiens | 5 | ALA4819109 | tissue-based format | Scientific Literature | |
4. | ALA4822367 | Functional | Growth inhibition of human MCF7 cells by MTT assay | Homo sapiens | 5 | ALA4819109 | cell-based format | Scientific Literature | |
5. | ALA4822368 | ADME | Growth inhibition of human Mesenchymal stem cells by MTT assay | Homo sapiens | 5 | ALA4819109 | tissue-based format | Scientific Literature | |
6. | ALA4822369 | Functional | Growth inhibition of human MDA-MB-231 cells by MTT assay | Homo sapiens | 5 | ALA4819109 | cell-based format | Scientific Literature | |
7. | ALA4822370 | Functional | Induction of apoptosis in human MCF7 cells assessed as viable cells at 100 nM incubated for 48 hrs by AnnexinV/PI staining based flow cytometry | Homo sapiens | 1 | ALA4819109 | cell-based format | Scientific Literature | |
8. | ALA4822371 | Functional | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 100 nM incubated for 48 hrs by AnnexinV/PI staining based flow cytometry | Homo sapiens | 1 | ALA4819109 | cell-based format | Scientific Literature | |
9. | ALA4822372 | Functional | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 100 nM incubated for 48 hrs by AnnexinV/PI staining based flow cytometry | Homo sapiens | 1 | ALA4819109 | cell-based format | Scientific Literature | |
10. | ALA4822373 | Functional | Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 100 nM incubated for 48 hrs by AnnexinV/PI staining based flow cytometry | Homo sapiens | 1 | ALA4819109 | cell-based format | Scientific Literature | |
11. | ALA4822374 | Binding | Activation of KM2 in human MCF7 cells assessed as increase in tetramer formation at 100 nM measured after 48 hrs by DSS cross linker assay | Homo sapiens | 1 | ALA4819109 | cell-based format | Scientific Literature | |
12. | ALA4822375 | Binding | Activation of PKM2 (unknown origin) assessed as increase in tetramer formation by measuring scattering by Dynamic Light Scattering assay | Homo sapiens | 1 | ALA4819109 | single protein format | Scientific Literature | |
13. | ALA5133617 | Binding | Activation of PKM2 in human CAL-27 cells measured after 3 hrs | Homo sapiens | 2 | ALA5131435 | cell-based format | Scientific Literature | |
14. | ALA5133618 | Binding | Activation of PKM2 in human CAL-27 cells assessed as increased in TPI1 activity at 12.5 to 50 nM measured after 3 hrs | Homo sapiens | 1 | ALA5131435 | cell-based format | Scientific Literature | |
15. | ALA5133620 | Binding | Activation of PKM2 in human CAL-27 cells assessed as decrease in GSH level at 12.5 to 50 nM | Homo sapiens | 1 | ALA5131435 | cell-based format | Scientific Literature | |
16. | ALA5133622 | Binding | Activation of PKM2 in human CAL-27 cells assessed as decrease in NADP+/NADPH ratio at 12.5 to 50 nM | Homo sapiens | 1 | ALA5131435 | cell-based format | Scientific Literature | |
17. | ALA5133624 | Binding | Activation of PKM2 in human CAL-27 cells assessed as decrease in lactate levels at 12.5 to 50 nM | Homo sapiens | 1 | ALA5131435 | cell-based format | Scientific Literature |