| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835313 | B | Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometry | Homo sapiens | 55 | single protein format | Scientific Literature | ||
| 2. | ALA4835315 | B | Inhibition of recombinant human pancreatic CPB incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4835316 | A | Fraction unbound in mouse plasma | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 4. | ALA4835317 | A | Fraction unbound in rat plasma | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 5. | ALA4835318 | A | Fraction unbound in human plasma | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 6. | ALA4835319 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4835320 | A | Renal clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4835321 | A | Metabolic stability in rat microsomes assessed as parent compound remaining | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 9. | ALA4835322 | A | Metabolic stability in mouse microsomes assessed as parent compound remaining | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 10. | ALA4835323 | A | Metabolic stability in human microsomes assessed as parent compound remaining | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 11. | ALA4835324 | A | Metabolic stability in rat Hepatocyte assessed as parent compound remaining | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 12. | ALA4835325 | A | Metabolic stability in mouse Hepatocyte assessed as parent compound remaining | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA4835326 | A | Metabolic stability in human Hepatocyte assessed as parent compound remaining | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA4835327 | B | Inhibition of recombinant human plasma CPN incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4835328 | A | AUC in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4835329 | A | Terminal half life in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4835330 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4835331 | B | Selectivity index, ratio of Ki for human pancreatic CPB to Ki for recombinat human activated TAFI | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4835332 | B | Selectivity index, ratio of Ki for human plasma CPN to Ki for recombinat human activated TAFI | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4835333 | B | Inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.8 uM incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysis relative to control | Rattus norvegicus | 14 | tissue-based format | Scientific Literature |
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