| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4834988 | B | Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km concentration by HTRF assay | Homo sapiens | 60 | protein complex format | Scientific Literature | ||
| 2. | ALA4834989 | B | Inhibition of recombinant UAE (unknown origin) in presence of ATP at Km concentration by HTRF assay | Homo sapiens | 60 | assay format | Scientific Literature | ||
| 3. | ALA4834990 | B | Inhibition of recombinant NAE (unknown origin) in presence of ATP at Km concentration by HTRF assay | Homo sapiens | 60 | protein complex format | Scientific Literature | ||
| 4. | ALA4834991 | B | Inhibition of SAE (unknown origin) using SUMO1 as substrate incubated for 60 mins in presence of ATP and PPi by pyrophosphate exchange assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 5. | ALA4834992 | B | Inhibition of SAE (unknown origin) using SUMO2 as substrate incubated for 60 mins in presence of ATP and PPi by pyrophosphate exchange assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 6. | ALA4834993 | B | Inhibition of UAE (unknown origin) using Ub as substrate incubated for 60 mins in presence of ATP and PPi by pyrophosphate exchange assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 7. | ALA4834994 | B | Inhibition of NAE (unknown origin) using Nedd-8 as substrate incubated for 60 mins in presence of ATP and PPi by pyrophosphate exchange assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 8. | ALA4834995 | B | Inhibition of SAE in human HCT116 cells assessed as reduction in conjugation of SUMO proteins to UBC9 by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4834996 | B | Inhibition of UAE in human HCT116 cells assessed as reduction in conjugation of ubiquitin to UBC12 by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4834997 | B | Inhibition of NAE in human HCT116 cells assessed as reduction in conjugation of Nedd8 to UBC10 by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4834998 | B | Inhibition of SAE in human HCT116 cells assessed as reduction in redistribution of SUMO2/3 proteins from nucleus to cytosol incubated for 4 hrs by immunofluorescence assay | Homo sapiens | 59 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!