# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4816175 | B | Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at 20 uM at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 17 | subcellular format | Scientific Literature | ||
2. | ALA4816176 | B | Inhibition of human ASAH1 stably over expressed in human A-375 cell lysate using RBM14C12 fluorogenic substrate measured at 1:1 compound to substrate molar ratio at pH 4.5 by fluorescence spectrophotometry | Homo sapiens | 17 | subcellular format | Scientific Literature | ||
3. | ALA4816178 | B | Inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 fluorogenic substrate measured at pH 9 in presence of Ca2+ by fluorescence spectrophotometry | Mus musculus | 2 | subcellular format | Scientific Literature | ||
4. | ALA4816179 | B | Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate | Homo sapiens | 4 | subcellular format | Scientific Literature | ||
5. | ALA4816180 | B | Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrate | Mus musculus | 2 | subcellular format | Scientific Literature | ||
6. | ALA4816181 | B | Inhibition of human ASAH1 stably over expressed in human intact A-375 cells using RBM14C12 fluorogenic substrate measured at pH 4.5 by fluorescence spectrophotometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4816182 | B | Inhibition of ACER3 in ASAH2-null intact mouse embryonic fibroblast cell assessed as reduction in sphingosine level incubated for 3 hrs by LC-MS analysis | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
8. | ALA4816183 | B | Inhibition of ACER3 in ASAH2-null intact mouse embryonic fibroblast cell assessed as reduction in sphingomyelin level incubated for 3 hrs by LC-MS analysis | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
9. | ALA4816184 | B | Inhibition of ACER3 in ASAH2-null intact mouse embryonic fibroblast cell assessed as reduction in glucosylceramide level incubated for 3 hrs by LC-MS analysis | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
10. | ALA4816185 | B | Inhibition of ACER3 in ASAH2-null intact mouse embryonic fibroblast cell assessed as increase in total ceramidase level incubated for 3 hrs by LC-MS analysis | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
11. | ALA4816191 | B | Inhibition of human ASAH2 stably over expressed in human HT-29 cell lysate using RBM14C24 fluorogenic substrate measured at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 4 | subcellular format | Scientific Literature | ||
12. | ALA4816192 | B | Inhibition of human ASAH2 stably over expressed in human HT29 cell lysate using RBM14C24 fluorogenic substrate measured at >40 uM at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
13. | ALA4816195 | B | Inhibition of ASAH2 in wild type mouse intact embryonic fibroblast using RBM14C16 fluorogenic substrate measured at pH 7.5 incubated for 3 hrs by fluorescence spectrophotometry | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
14. | ALA4816196 | B | Inhibition of ACER3 in ASAH2-null mouse intact embryonic fibroblast using RBM14C16 fluorogenic substrate measured at pH 9 for 3 hrs by fluorescence spectrophotometry | Mus musculus | 4 | tissue-based format | Scientific Literature |