| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4822871 | F | Induction of apoptosis in human TMD8 cells assessed as early apoptotic cells at 0.5 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 4.35%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4822872 | F | Induction of apoptosis in human TMD8 cells assessed as viable cells at 0.5 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 94.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4822873 | F | Induction of apoptosis in human TMD8 cells assessed as necrotic cells at 0.25 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 0%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4822874 | F | Induction of apoptosis in human TMD8 cells assessed as late apoptotic cells at 0.25 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 1.44%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4822875 | F | Induction of apoptosis in human TMD8 cells assessed as early apoptotic cells at 0.25 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 4.35%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4822876 | B | Inhibition of N-terminal GST-fused human full length recombinant MNK1 (1 to 424 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate at 500 nM preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA4822877 | B | Inhibition of N-terminal GST-fused human full length recombinant MNK2 (1 to 465 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate at 500 nM preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 8. | ALA4822878 | B | Inhibition of N-terminal GST-fused human full length recombinant MNK1 (1 to 424 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 9. | ALA4822879 | B | Inhibition of N-terminal GST-fused human full length recombinant MNK2 (1 to 465 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 10. | ALA4822880 | F | Antiproliferative activity against human TMD8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 11. | ALA4822881 | F | Antiproliferative activity against human DOHH-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 12. | ALA4822882 | B | Inhibition of BTK (unknown origin) at 500 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4822883 | B | Inhibition of CDK1 (unknown origin) at 500 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4822884 | B | Inhibition of IRAK4 (unknown origin) at 500 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4822885 | B | Inhibition of AMPK (unknown origin) at 500 nM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA4822886 | B | Inhibition of JAK1 (unknown origin) at 500 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4822887 | B | Inhibition of CSF1R (unknown origin) at 500 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4822888 | F | Induction of apoptosis in human TMD8 cells assessed as viable cells at 0.25 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 94.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4822889 | F | Induction of apoptosis in human TMD8 cells assessed as late apoptotic cells at 0.5 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 1.44%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4822890 | F | Induction of apoptosis in human TMD8 cells assessed as necrotic cells at 0.5 uM incubated for 24 hrs by AnnexinV-FITC/PE staining based flow cytometry (Rvb = 0%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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