# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4844509 | Binding | Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter method | Homo sapiens | 20 | ALA4842370 | cell membrane format | Scientific Literature | |
2. | ALA4844510 | Functional | Antagonist activity at human 5HT6R expressed in 1321N1 cells assessed as inhibition of IBMX-induced cAMP production measured after 30 mins by TR-FRET assay | Homo sapiens | 6 | ALA4842370 | cell-based format | Scientific Literature | |
3. | ALA4844511 | Binding | Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophotometric based Ellman's method | Equus caballus | 22 | ALA4842370 | cell-free format | Scientific Literature | |
4. | ALA4844512 | Binding | Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophotometric based Ellman's method | Electrophorus electricus | 21 | ALA4842370 | single protein format | Scientific Literature | |
5. | ALA4844513 | Binding | Irreversible inhibition of recombinant equine serum BChE using butyrylthiocholine as substrate preincubated up to 120 mins by DTNB-reagent based 100-fold dilution assay | Equus caballus | 7 | ALA4842370 | cell-free format | Scientific Literature | |
6. | ALA4844514 | Binding | Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation at 10 uM incubated up to 48 hrs under shaking condition and measured every 3 min by Thioflavin T based fluorescence assay relative to control | Homo sapiens | 20 | ALA4842370 | single protein format | Scientific Literature | |
7. | ALA4844516 | Binding | Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 24 hrs by microplate reader assay relative to control | Homo sapiens | 12 | ALA4842370 | assay format | Scientific Literature | |
8. | ALA4844517 | Binding | Inhibition of tau protein (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 24 hrs by microplate reader assay relative to control | Homo sapiens | 12 | ALA4842370 | assay format | Scientific Literature |