# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835172 | Binding | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Homo sapiens | 60 | ALA4834410 | single protein format | Scientific Literature | |
2. | ALA4835206 | Binding | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in absence of serum by biochemical assay | Homo sapiens | 3 | ALA4834410 | single protein format | Scientific Literature | |
3. | ALA4835207 | Binding | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in presence of 2% HSA by biochemical assay | Homo sapiens | 3 | ALA4834410 | single protein format | Scientific Literature | |
4. | ALA4835208 | Binding | Ratio of IC50 for human recombinant ADAMTS-5 in presence of 2% HSA to human recombinant ADAMTS-5 in absence of serum | Homo sapiens | 3 | ALA4834410 | assay format | Scientific Literature | |
5. | ALA4835209 | ADME | Plasma protein binding in human at 5 uM measured after 4 hrs by LC-MS/MS analysis | Homo sapiens | 6 | ALA4834410 | cell-free format | Scientific Literature |