# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835172 | B | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Homo sapiens | 60 | single protein format | Scientific Literature | ||
2. | ALA4835206 | B | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in absence of serum by biochemical assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA4835207 | B | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in presence of 2% HSA by biochemical assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
4. | ALA4835208 | B | Ratio of IC50 for human recombinant ADAMTS-5 in presence of 2% HSA to human recombinant ADAMTS-5 in absence of serum | Homo sapiens | 3 | assay format | Scientific Literature | ||
5. | ALA4835209 | A | Plasma protein binding in human at 5 uM measured after 4 hrs by LC-MS/MS analysis | Homo sapiens | 6 | cell-free format | Scientific Literature |