# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4818717 | Binding | Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate at 100 uM by Ellman's method | Homo sapiens | 1 | ALA4814070 | single protein format | Scientific Literature | |
2. | ALA4818718 | Binding | Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity at 100 uM by Ellman's method | Homo sapiens | 2 | ALA4814070 | single protein format | Scientific Literature | |
3. | ALA4818724 | Binding | Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV holding potential by whole-cell patch clamp method | Homo sapiens | 31 | ALA4814070 | cell-based format | Scientific Literature | |
4. | ALA4818726 | Binding | Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV holding potential by whole-cell patch clamp method | Homo sapiens | 31 | ALA4814070 | cell-based format | Scientific Literature | |
5. | ALA4818727 | Binding | Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current at 100 uM measured at +40 mV holding potential by whole-cell patch clamp method | Homo sapiens | 30 | ALA4814070 | cell-based format | Scientific Literature | |
6. | ALA4818728 | Binding | Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current at 100 uM measured at +40 mV holding potential by whole-cell patch clamp method | Homo sapiens | 31 | ALA4814070 | cell-based format | Scientific Literature |