| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4831021 | B | Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 2. | ALA4831022 | B | Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 3. | ALA4831029 | F | Antiproliferative activity against human MOLM-14 cells harboring FLT3-ITD mutant assessed as cell growth inhibition by resazurin assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA4831030 | F | Antiproliferative activity against human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as cell growth inhibition by resazurin assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4831031 | F | Antiproliferative activity against human MOLM-14 cells harboring FLT3-ITD F691L mutant assessed as cell growth inhibition by resazurin assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4831032 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as live cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 96.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4831033 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as early apoptotic cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 2.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4831034 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as late apoptotic cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 1.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4831035 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as live cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 97.0%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4831036 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as early apoptotic cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4831037 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as late apoptotic cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4831038 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD mutant assessed as dead cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 0.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4831039 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as live cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 97.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4831040 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as early apoptotic cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4831041 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as late apoptotic cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 1.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4831042 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as live cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 96.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4831043 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as early apoptotic cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 2.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4831044 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD D835Y mutant assessed as late apoptotic cells at 1 uM measured after 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 0.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4831045 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD F691L mutant assessed as live cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 96.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4831046 | F | Induction of apoptosis in human MOLM-14 cells harboring FLT3-ITD F691L mutant assessed as early apoptotic cells at 1 uM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 2.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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