# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4807527 | B | Inhibition of BODIPY-FL-labeled AT-7519 binding to human His-tagged CDK12/CycK assessed as BODIPY-FL-labeled AT-7519 binding by measuring fluorescence intensity at 1 uM incubated for 120 mins in presence of 3 uM BODIPY-FL-labeled AT-7519 by TR-FRET assay relative to control | Homo sapiens | 51 | protein complex format | Patent Bioactivity Data | ||
2. | ALA4807529 | B | Inhibition of human His-tagged CDK12/CycK using ULight-labeled eIF4E-binding protein 1 substrate at 1 uM incubated for 60 mins by fluorescence based assay relative to control | Homo sapiens | 26 | protein complex format | Patent Bioactivity Data | ||
3. | ALA4807530 | B | Inhibition of human CDK12/CycK in human A2780 cells assessed as intracellular phosphorylated CTD Ser2 art 1 uM by In-Cell Western method relative to control | Homo sapiens | 26 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4807531 | F | Antiproliferative activity against human A2780 cells at 1 uM by CellTiter-Glo reagent assay relative to control | Homo sapiens | 49 | cell-based format | Patent Bioactivity Data |