#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4812388	Binding	Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaphorase/resazurin-coupled system	Homo sapiens	91	ALA4811250	single protein format	Scientific Literature
2.	ALA4812390	Binding	Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaphorase/resazurin-coupled system	Homo sapiens	77	ALA4811250	single protein format	Scientific Literature
3.	ALA4812392	ADME	Metabolic stability in rat liver microsomes assessed as half life incubated for 15 mins by high resolution LC/MS analysis	Rattus norvegicus	13	ALA4811250	microsome format	Scientific Literature
4.	ALA4812393	ADME	Permeability of compound at pH 7.4 by PAMPA assay		13	ALA4811250	assay format	Scientific Literature
5.	ALA4812394	Physicochemical	Kinetic solubility of the compound in pH 7.4 phosphate buffer measured after 6 hrs by UV spectroscopy		13	ALA4811250	small-molecule physicochemical format	Scientific Literature
6.	ALA4812395	Binding	Inhibition of IDH1 R132H mutant (unknown origin) expressed in human U87 cells assessed as R-2-hydroxyglutarate production at 100 nM after 48 hrs by LC-MS analysis	Homo sapiens	11	ALA4811250	cell-based format	Scientific Literature
7.	ALA4812396	Binding	Inhibition of IDH1 R132H mutant (unknown origin) expressed in human U87 cells assessed as R-2-hydroxyglutarate production at 500 nM after 48 hrs by LC-MS analysis	Homo sapiens	11	ALA4811250	cell-based format	Scientific Literature