# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4819975 | Binding | Inhibition of human BTK using poly (Glu,Tyr) as substrate in presence of ATP and Ci(gamma33-P) ATP measured by microplate reader assay | Homo sapiens | 14 | ALA4819006 | single protein format | Scientific Literature | |
2. | ALA4819976 | Binding | Inhibition of human BTK assessed as residual activity using poly (Glu,Tyr) as substrate in presence of ATP and Ci(gamma33-P) ATP at 1 uM measured by microplate reader assay | Homo sapiens | 13 | ALA4819006 | single protein format | Scientific Literature | |
3. | ALA4819977 | Binding | Inhibition of GST-tagged CDK2/cyclinE (unknown origin) expressed in Sf9 cells assessed as residual activity using histone H1 as substrate in presence of ATP and Ci(gamma33-P) ATP at 1 uM measured by microplate reader assay | Homo sapiens | 14 | ALA4819006 | cell-based format | Scientific Literature | |
4. | ALA4819978 | Binding | Inhibition of human recombinant GST-tagged SYK (M1 to N635 residues) assessed as residual activity using poly (Glu,Tyr) as substrate in presence of ATP and Ci(gamma33-P) ATP at 1 uM measured by microplate reader assay | Homo sapiens | 14 | ALA4819006 | single protein format | Scientific Literature | |
5. | ALA4819979 | Binding | Inhibition of human recombinant full length GST-tagged FYN (M1 to L537 residues) assessed as residual activity using poly (Glu,Tyr) as substrate in presence of ATP and Ci(gamma33-P) ATP at 1 uM measured by microplate reader assay | Homo sapiens | 14 | ALA4819006 | single protein format | Scientific Literature | |
6. | ALA4819980 | Binding | Inhibition of human recombinant full length N-terminal GST-tagged FLT3 (R571 to S993 residues) assessed as residual activity using poly (Ala, Glu, Lys, Tyr) hydrobromide as substrate in presence of ATP and Ci(gamma33-P) ATP at 1 uM measured by microplate reader assay | Homo sapiens | 14 | ALA4819006 | single protein format | Scientific Literature | |
7. | ALA4819981 | Binding | Inhibition of Abl (unknown origin) expressed in Sf9 cells assessed as residual activity using GGEAIYAAPFKK peptide as substrate in presence of ATP and Ci(gamma33-P)ATP at 1 uM measured by microplate reader | Homo sapiens | 13 | ALA4819006 | cell-based format | Scientific Literature | |
8. | ALA4819982 | Functional | Growth inhibition of human Ramos cells assessed as inhibition of cell growth measured after 72 hrs by resazurin dye based assay | Homo sapiens | 16 | ALA4819006 | cell-based format | Scientific Literature | |
9. | ALA4819983 | Functional | Growth inhibition of human K562 cells assessed as inhibition of cell growth measured after 72 hrs by resazurin dye based assay | Homo sapiens | 16 | ALA4819006 | cell-based format | Scientific Literature | |
10. | ALA4819984 | Functional | Growth inhibition of human REC1 cells assessed as inhibition of cell growth measured after 72 hrs by resazurin dye based assay | Homo sapiens | 16 | ALA4819006 | cell-based format | Scientific Literature | |
11. | ALA4819985 | Functional | Growth inhibition of human patient derived UPF1H cells assessed as inhibition of cell growth measured after 72 hrs by resazurin dye based assay | Homo sapiens | 16 | ALA4819006 | tissue-based format | Scientific Literature | |
12. | ALA4819986 | Functional | Growth inhibition of human patient derived UPF7U cells assessed as inhibition of cell growth measured after 72 hrs by resazurin dye based assay | Homo sapiens | 16 | ALA4819006 | tissue-based format | Scientific Literature | |
13. | ALA4819989 | Binding | Inhibition of BTK in human Ramos cells assessed as reduction of IgM stimulated BTK (Y323) phosphorylation at 1 to 5 uM measured after 24 hrs by western blot assay | Homo sapiens | 4 | ALA4819006 | cell-based format | Scientific Literature | |
14. | ALA4819990 | Binding | Inhibition of BTK in human Ramos cells assessed as reduction of IgM stimulated PLCgamma2 (Y1217) phosphorylation at 1 to 5 uM measured after 24 hrs by western blot assay | Homo sapiens | 4 | ALA4819006 | cell-based format | Scientific Literature | |
15. | ALA4820001 | Binding | Inhibition of ERK1/2 in human Ramos cells assessed as reduction in ERK1/2 phosphorylation at 1 to 5 uM measured after 24 hrs by western blot assay | Homo sapiens | 4 | ALA4819006 | cell-based format | Scientific Literature |