# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4840233 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as induction of CDK4 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA4840234 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as induction of CDK6 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA4840235 | B | Protac activity at CRBN/IKZF3 in human MM1.S cells assessed as induction of IKZF3 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4840236 | F | Cytotoxicity against human MM1.S cells assessed as effect on cell viability at 0.1 to 10 uM incubated for 72 hrs by luminescence based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4840238 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4840239 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4840240 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA4840241 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4840242 | B | Protac activity at CRBN/IKZF1 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4840243 | B | Protac activity at CRBN/IKZF1 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4840244 | B | Protac activity at CRBN/IKZF3 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA4840245 | B | Protac activity at CRBN/IKZF3 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature |