# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA695094 | B | Binding affinity against Heat shock 90 KD protein (Hsp90) | 1 | protein format | Scientific Literature | |||
2. | ALA693501 | B | The compound was tested for binding affinity against isolated N-domain of Heat shock protein HSP 90 | Fungi | 1 | single protein format | Scientific Literature | ||
3. | ALA693502 | B | The compound was tested for binding affinity against yeast Heat shock protein HSP 90 | Fungi | 1 | single protein format | Scientific Literature | ||
4. | ALA878183 | F | Compound was evaluated for antiproliferative activity against human ovarian carcinoma cell line A2780. | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA715090 | F | Inhibition of steady-state expression of ER in MCF-7 breast cancer cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA715091 | F | Inhibition of steady-state expression of HER2 in MCF-7 breast cancer cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA715092 | F | Inhibition of steady-state expression of Raf-1 in MCF-7 breast cancer cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA719302 | F | In vivo inhibition of phospho-p185erbB-2 expression in human SK-BR-3 tumors at 100 mg/kg ip dose in mice | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA873150 | F | In vivo inhibition of phospho-p185erbB-2 expression in human SK-BR-3 tumors at 200 mg/kg dose ip in mice | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA719226 | F | In vivo inhibition of phospho-p185erbB-2 expression in human SK-BR-3 tumors at 400 mg/kg dose in mice (lethal) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA719228 | F | In vivo inhibition of phospho-p185erbB-2 expression in human SK-BR-3 tumors at 50 mg/kg ip dose in mice | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA723638 | F | In vivo inhibition of p185 phosphotyrosine in nu/nu nude mice bearing Fisher rat embryo cells transfected with human erbB-2 (inactive) | Mus musculus | 13 | organism-based format | Scientific Literature | ||
13. | ALA806403 | F | Inhibition of oncogene product p185 erbB-2 from human breast cancer cells(SK-BR-3 cells) at 50 mg/kg dose. | 81 | organism-based format | Scientific Literature | |||
14. | ALA806578 | F | In vitro inhibition of p185 erbB-2 oncoprotein in human breast cancer SK-BR-3 cells | Homo sapiens | 53 | cell-based format | Scientific Literature | ||
15. | ALA824222 | F | Inhibition of proliferation in NCI panel of 60 human cell lines (Range is 20-80 uM) | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
16. | ALA828486 | F | Inhibition of yeast Hsp90 ATPase activity | Saccharomyces cerevisiae | 18 | assay format | Scientific Literature | ||
17. | ALA831277 | F | Inhibition of yeast Hsp90 ATPase activity at 40 uM | Saccharomyces cerevisiae | 13 | assay format | Scientific Literature | ||
18. | ALA832187 | F | Effective concentration for Her-2 degradation in SKBR-3 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA824782 | F | Inhibition of HCT116 human colon cancer cell proliferation | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
20. | ALA834676 | F | Inhibitory concentration against human leukemia K562 cell lines | Homo sapiens | 5 | cell-based format | Scientific Literature |