# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA665216 | Binding | Ability to inhibit cytoplasmic malate dehydrogenase; Inactive | 14 | ALA1122163 | single protein format | Scientific Literature | ||
2. | ALA673295 | Functional | Inhibition of Ehrlich ascites cell respiration | Mus musculus | 19 | ALA1122163 | cell-based format | Scientific Literature | |
3. | ALA706200 | Binding | Ability to inhibit skeletal muscle LDH (LDH-M4); Inactive | Plasmodium falciparum | 20 | ALA1122163 | tissue-based format | Scientific Literature | |
4. | ALA734262 | Binding | Ability to inhibit mitochondrial malate dehydrogenase; Inactive | 2 | ALA1122163 | single protein format | Scientific Literature | ||
5. | ALA908907 | Binding | Residual activity of human CK2 at 30 uM | Homo sapiens | 42 | ALA1137306 | protein complex format | Scientific Literature | |
6. | ALA1112854 | Functional | Antioxidant activity assessed as residual ABTS cationic radical scavenging activity at 1.5 mM after 30 mins relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
7. | ALA1112855 | Functional | Antioxidant activity assessed as residual galvinoxyl radical scavenging activity at 1.5 mM after 30 mins relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
8. | ALA1112856 | Functional | Antioxidant activity assessed as residual DPPH radical scavenging activity at 1.5 mM after 30 mins relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
9. | ALA1112857 | Functional | Antioxidant activity against AAPH-induced linoleic acid oxidation assessed as exhausted methyl linoleate at 2 mM after 4 hrs relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
10. | ALA1112858 | Functional | Antioxidant activity against beta-carotene bleaching assessed as decrease of absorbance at 0.3 mM after 100 mins relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
11. | ALA1112859 | Functional | Antioxidant activity against hydroxyl radical-induced DNA damage assessed as TBARS production at 400 uM after 30 mins relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
12. | ALA1112860 | Functional | Antioxidant activity against AAPH-induced DNA damage assessed as TBARS production at 200 uM after 4 hrs relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
13. | ALA1112861 | Functional | Antioxidant activity against Cu(2+)/GSH-induced DNA damage assessed as TBARS production at 200 uM after 4 hrs relative to control | 6 | ALA1157847 | assay format | Scientific Literature | ||
14. | ALA3280958 | Functional | Inhibition of respiration in mouse Ehrlich ascites cells after 30 mins incubation at 37 degC by whole cell model | Mus musculus | 15 | ALA3271955 | cell-based format | Scientific Literature | |
15. | ALA3280960 | Physicochemical | Lipophilicity, log P of the compound | 1 | ALA3271955 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA4121205 | Binding | Inhibition of Rickettsia prowazekii N-terminal His6-tagged methionine aminopeptidase 1 expressed in Escherichia coli DLB3 Rosetta cells at 10 uM using Met-AMC as substrate preincubated for 1 hr followed by 30 mins incubation after substrate addition measured after 90 mins in presence of MnCl2 by fluorescence assay relative to control | Rickettsia prowazekii | 288 | ALA4118110 | cell-based format | Scientific Literature | |
17. | ALA4354684 | Binding | Inhibition of RyR1 harboring R2163C mutant (unknown origin) stably expressed in HEK293 cells coexpressing R-CEPIA1er assessed as suppression in Ca2+ leakage from ER prestimulated with doxycycline for 24 to 28 hrs followed by compound addition at 100 secs and measured every 10 secs for 300 secs by time lapse fluorimetry based Michelis-Menten analysis | Homo sapiens | 33 | ALA4351027 | cell-based format | Scientific Literature | |
18. | ALA4354685 | Binding | Inhibition of RyR1 harboring R2163C mutant (unknown origin) stably expressed in HEK293 cells coexpressing R-CEPIA1er assessed as suppression in Ca2+ leakage from ER up to 30 uM prestimulated with doxycycline for 24 to 28 hrs followed by compound addition at 100 secs and measured every 10 secs for 300 secs by fluorometric analysis | Homo sapiens | 1 | ALA4351027 | cell-based format | Scientific Literature | |
19. | ALA5136434 | Binding | Binding affinity to DC-SIGN ECD (66 to 404 residue) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by STD reporter assay based NMR spectroscopy analysis | Homo sapiens | 26 | ALA5131554 | assay format | Scientific Literature |