# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651284 | F | In vitro cytotoxicity against Plasmodium falciparum infected BC cell line. | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA663727 | B | Binding affinity towards mutant dihydrofolate reductase (A16V+S108T DHFR) of Plasmodium falciparum. | Plasmodium falciparum | 25 | single protein format | Scientific Literature | ||
3. | ALA663728 | B | Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
4. | ALA667200 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
5. | ALA880697 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
6. | ALA704856 | F | In vitro cytotoxicity against Plasmodium falciparum infected KB cell line | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
7. | ALA760281 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase A16V/S108T (T9/94RC17) mutant | Plasmodium falciparum | 15 | assay format | Scientific Literature | ||
8. | ALA760283 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase C59R/S108N (K1CB1) mutant | Plasmodium falciparum | 17 | assay format | Scientific Literature | ||
9. | ALA760860 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase C59R+S108N/I164L (Csl-2) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
10. | ALA765484 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase CN51I/C59R/S108N/I164L (V1/S) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
11. | ALA765485 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase N51I/C59R/S108N (W2) | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
12. | ALA765486 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase wild type (TM4/8.2) | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
13. | ALA812732 | F | In vitro cytotoxicity against Plasmodium falciparum infected vero cell line. | Chlorocebus sabaeus | 26 | cell-based format | Scientific Literature | ||
14. | ALA821377 | B | Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum. | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
15. | ALA847341 | B | Ratio of binding affinity for mutant (A16V+S108T) to that of wild type dihydrofolate reductase | Plasmodium falciparum | 25 | single protein format | Scientific Literature | ||
16. | ALA847342 | B | Ratio of binding affinity for mutant (C59R+S108N+I164L) to that of wild type dihydrofolate reductase | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
17. | ALA847343 | B | Ratio of binding affinity for mutant (N51I+C59R+S108N) to that of wild type dihydrofolate reductase | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
18. | ALA847344 | B | Ratio of binding affinity for mutant (N51I+C59R+S108N+I164L) to that of wild type dihydrofolate reductase | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
19. | ALA838937 | F | Relative antiplasmodial activity to cytotoxicity in Plasmodium falciparum Csl-2 infected BC cells | 26 | cell-based format | Scientific Literature | |||
20. | ALA838938 | F | Relative antiplasmodial activity to cytotoxicity in Plasmodium falciparum Csl-2 infected KB cells | 26 | cell-based format | Scientific Literature |