# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615705 | Functional | Tested for 5-HT 3 receptor antagonist potency by ability to inhibit the reflex bradycardia, the Bezold-Jarisch reflex in the rat | 7 | ALA1126614 | assay format | Scientific Literature | ||
2. | ALA615707 | Functional | Relative ability to increase cholinergically mediated contractions in isolated ileum of guinea pig | Cavia porcellus | 8 | ALA1126614 | tissue-based format | Scientific Literature | |
3. | ALA615708 | Functional | Stimulatory activity of intragastric pressure was tested in the rat | 6 | ALA1126614 | assay format | Scientific Literature | ||
4. | ALA615403 | Binding | The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortex | 6 | ALA1125444 | assay format | Scientific Literature | ||
5. | ALA617681 | Binding | The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brain | 6 | ALA1125444 | assay format | Scientific Literature | ||
6. | ALA619795 | Binding | The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortices | 3 | ALA1125444 | tissue-based format | Scientific Literature | ||
7. | ALA618920 | Binding | Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptor | Rattus norvegicus | 11 | ALA1136809 | assay format | Scientific Literature | |
8. | ALA619076 | Binding | Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptor | Cavia porcellus | 11 | ALA1136809 | tissue-based format | Scientific Literature | |
9. | ALA619021 | Functional | Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosae | 6 | ALA1152038 | tissue-based format | Scientific Literature | ||
10. | ALA619025 | Functional | Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus strip assay | 6 | ALA1126380 | tissue-based format | Scientific Literature | ||
11. | ALA619031 | Binding | Relaxation of carbachol induced contractions of rat tunica muscularis mucosae | 14 | ALA1125444 | single protein format | Scientific Literature | ||
12. | ALA619034 | Binding | Tested for its efficacy against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosae | 6 | ALA1152038 | tissue-based format | Scientific Literature | ||
13. | ALA875080 | Binding | Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortex | 6 | ALA1152038 | assay format | Scientific Literature | ||
14. | ALA620719 | Functional | Compound was evaluated in vivo for the antagonistic activity towards 5-hydroxytryptamine 3 receptor | 6 | ALA1126380 | organism-based format | Scientific Literature | ||
15. | ALA644242 | Binding | The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brain | 6 | ALA1125444 | assay format | Scientific Literature | ||
16. | ALA648165 | Binding | The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortex | 6 | ALA1125444 | assay format | Scientific Literature | ||
17. | ALA651237 | Binding | The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brain | 6 | ALA1125444 | assay format | Scientific Literature | ||
18. | ALA667037 | Binding | The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striata | 6 | ALA1125444 | assay format | Scientific Literature | ||
19. | ALA672457 | Binding | Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligand | Rattus norvegicus | 9 | ALA1136809 | tissue-based format | Scientific Literature | |
20. | ALA673620 | Binding | The ability to inhibit [3H]domperidone binding to dopamine receptor D2 in rat striata | 6 | ALA1125444 | assay format | Scientific Literature |