| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA679308 | B | Compound was evaluated for the kinetic constant for the inhibition of Gamma-amino-N-butyrate transaminase | Sus scrofa | 5 | single protein format | Scientific Literature | ||
| 2. | ALA679310 | B | Compound was evaluated for the competitive inhibition of of Gamma-amino-N-butyrate transaminase | Sus scrofa | 9 | single protein format | Scientific Literature | ||
| 3. | ALA679315 | B | Compound was evaluated for the kinetic constant for the inactivation of Gamma-amino-N-butyrate transaminase | Sus scrofa | 5 | single protein format | Scientific Literature | ||
| 4. | ALA849833 | B | Selectivity ratio of Kinact/KI | 4 | assay format | Scientific Literature | |||
| 5. | ALA4731051 | B | Mechanism based inactivation of pig brain GABA-AT assessed as inactivation rate constant using GABA as substrate in presence of NADP+ and alpha-ketoglutarate by SSDH coupled enzyme based UV-Vis spectrophotometry | Sus scrofa | 5 | assay format | Scientific Literature | ||
| 6. | ALA4731052 | B | Binding affinity pig brain GABA-AT assessed as inactivation constant using GABA as substrate in presence of NADP+ and alpha-ketoglutarate by SSDH coupled enzyme based UV-Vis spectrophotometry | Sus scrofa | 7 | assay format | Scientific Literature | ||
| 7. | ALA4731053 | B | Mechanism based inactivation of pig brain GABA-AT assessed as ratio of Kinact to Ki using GABA as substrate in presence of NADP+ and alpha-ketoglutarate by SSDH coupled enzyme based UV-Vis spectrophotometry | Sus scrofa | 5 | assay format | Scientific Literature | ||
| 8. | ALA4731055 | B | Inactivation of GABA-AT (unknown origin) assessed as partition ratio | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4731056 | B | Substrate activity at pig brain GABA-AT assessed as formation of M4 by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 10. | ALA4731057 | B | Substrate activity at pig brain GABA-AT assessed as formation of (S)-3-iminocyclopentanecarboxylic acid by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 11. | ALA4731058 | B | Substrate activity at pig brain GABA-AT assessed as formation of (S)-3-oxocyclopentanecarboxylic acid by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 12. | ALA4731059 | B | Substrate activity at pig brain GABA-AT assessed as formation of (1R,3S)-3-fluoro-4-oxocyclopentanecarboxylic acid by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 13. | ALA4731060 | B | Substrate activity at pig brain GABA-AT assessed as formation of PLP-bound M8 by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 14. | ALA4731061 | B | Substrate activity at pig brain GABA-AT assessed as formation of M5 in presence of PLP by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 15. | ALA4731062 | B | Substrate activity at pig brain GABA-AT assessed as formation of (1R,3S)-3-fluoro-4-((3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4(1H)-ylidene)methylimino)cyclopentanecarboxylic acid by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 16. | ALA4731063 | B | Substrate activity at pig brain GABA-AT assessed as formation of (S)-3-((3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl)methyleneamino)cyclopent-3-enecarboxylic acid by LC-MS/MS analysis | Sus scrofa | 1 | assay format | Scientific Literature | ||
| 17. | ALA4731067 | B | Inactivation of pig brain GABA-AT assessed as partition ratio by measuring number of molecules required for enzyme inactivation | Sus scrofa | 2 | assay format | Scientific Literature | ||
| 18. | ALA4731078 | B | Binding affinity to pig brain GABA-AT assessed as adduct formation by measuring change in protein mass by LC-MS/MS analysis | Sus scrofa | 4 | assay format | Scientific Literature |
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