# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5032402 | B | Inhibition of human FIH using HLEVVKLLLEAGADVNAQDK-CONH2 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by RapidFire Mass spectrometry assay | Homo sapiens | 13 | ALA5030566 | single protein format | Scientific Literature | |
2. | ALA5032403 | F | Antiproliferative activity against human OCI-AML-3 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
3. | ALA5032404 | B | Inhibition of recombinant human NO66 expressed in Escherichia coli BL21 (DE3) using RPL8 N205PVEHPFGGGNHQHIGKPST224 as substrate preincubated for 15 mins followed by substrate addition and measured after 30 to 60 mins by RapidFire Mass spectrometry assay | Homo sapiens | 16 | ALA5030566 | assay format | Scientific Literature | |
4. | ALA5032405 | B | Inhibition of recombinant human MINA53 expressed in Escherichia coli BL21 (DE3) using RPL27A G31RGNAGGLHHHRINFDKYHP49 as substrate preincubated for 15 mins followed by substrate addition and measured after 30 to 60 mins by RapidFire Mass spectrometry assay | Homo sapiens | 16 | ALA5030566 | assay format | Scientific Literature | |
5. | ALA5032406 | B | Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | cell-based format | Scientific Literature | |
6. | ALA5032407 | B | Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 mins followed by substrate addition and measured after 5 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | cell-based format | Scientific Literature | |
7. | ALA5032408 | B | Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | assay format | Scientific Literature | |
8. | ALA5032409 | B | Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 8 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | assay format | Scientific Literature | |
9. | ALA5032410 | B | Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | cell-based format | Scientific Literature | |
10. | ALA5032411 | B | Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 10 mins by Alphascreen assay | Homo sapiens | 13 | ALA5030566 | assay format | Scientific Literature | |
11. | ALA5032412 | F | Antiproliferative activity against human IMS-M2 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
12. | ALA5032413 | F | Antiproliferative activity against human OCI-AML2 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
13. | ALA5032414 | F | Antiproliferative activity against human MV4-11 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
14. | ALA5032415 | F | Antiproliferative activity against human Kasumi 1 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
15. | ALA5032416 | F | Antiproliferative activity against human U-937 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
16. | ALA5032418 | F | Antiproliferative activity against human NB-4 cells incubated for 48 hrs by WST-1 assay | Homo sapiens | 2 | ALA5030566 | cell-based format | Scientific Literature | |
17. | ALA5032420 | F | Antiproliferative activity against human HL-60 cells incubated for 48 hrs by WST-1 assay | Homo sapiens | 2 | ALA5030566 | cell-based format | Scientific Literature | |
18. | ALA5032421 | F | Antiproliferative activity against human KARPAS-299 cells at 100 uM incubated for 48 hrs by WST-1 assay | Homo sapiens | 3 | ALA5030566 | cell-based format | Scientific Literature | |
19. | ALA5032422 | F | Antiproliferative activity against human U-87 MG cells incubated for 72 to 120 hrs by MTT assay | Homo sapiens | 4 | ALA5030566 | cell-based format | Scientific Literature | |
20. | ALA5032423 | F | Antiproliferative activity against human MKN-45 cells at 10 to 100 uM incubated for 72 to 120 hrs by MTT assay | Homo sapiens | 4 | ALA5030566 | cell-based format | Scientific Literature |