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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5035841 F Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as inhibition of LPA stimulated calcium flux incubated for 20 mins followed by LPS stimulation and measured for 90 seconds Homo sapiens 36 cell-based format Scientific Literature 2. ALA5035842 A Protein binding in human plasma assessed as free fraction at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Homo sapiens 19 organism-based format Scientific Literature 3. ALA5035843 A Protein binding in Sprague-Dawley rat plasma assessed as free fraction at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Rattus norvegicus 18 organism-based format Scientific Literature 4. ALA5035844 A Protein binding in CD-1 mouse plasma assessed as free fraction at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Mus musculus 19 organism-based format Scientific Literature 5. ALA5035845 A Plasma clearance in CD-1 mouse at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 6. ALA5035846 A Plasma clearance in Sprague-Dawley rat at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 7. ALA5035847 A Inhibition of CYP2B6 (unknown origin) Homo sapiens 3 single protein format Scientific Literature 8. ALA5035848 A Plasma clearance in Cynomolgus monkey at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Macaca fascicularis 2 organism-based format Scientific Literature 9. ALA5035849 A Volume of distribution at steady state in CD-1 mouse at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 10. ALA5035850 A Oral bioavailability in CD-1 mouse at 3 mg/kg measured up to 24 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 11. ALA5035851 A Volume of distribution at steady state in Sprague-Dawley rat at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA5035852 A Volume of distribution at steady state in cynomolgus monkey at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Macaca fascicularis 2 organism-based format Scientific Literature 13. ALA5035853 A Oral bioavailability in Sprague-Dawley rat at 3 mg/kg measured up to 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA5035854 A Oral bioavailability in cynomolgus monkey at 3 mg/kg measured up to 24 hrs by LC-MS/MS analysis Macaca fascicularis 2 organism-based format Scientific Literature 15. ALA5035855 A Elimination half life in CD-1 mouse at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 16. ALA5035856 A Elimination half life in Sprague-Dawley rat at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 17. ALA5035857 A Elimination half life in cynomolgus monkey at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Macaca fascicularis 2 organism-based format Scientific Literature 18. ALA5035858 A Protein binding in Cynomolgus monkey plasma assessed as free fraction at 3 mg/kg, po or 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis Macaca fascicularis 2 organism-based format Scientific Literature 19. ALA5035859 F Antagonist activity at mouse LPA1 receptor expressed in CHO cells assessed as inhibition of LPA stimulated calcium flux incubated for 20 mins followed by LPA stimulation and measured for 90 seconds Mus musculus 3 cell-based format Scientific Literature 20. ALA5035860 F Antagonist activity at LPA1 receptor in human lung fibroblast cells assessed as inhibition of LPA stimulated calcium flux incubated for 20 mins followed by LPA stimulation and measured for 90 seconds Homo sapiens 3 tissue-based format Scientific Literature