| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5031917 | F | Analgesic activity in rat model of partial sciatic nerve ligation-induced neuropathic pain assessed as reversal of allodynia at 3 mg/kg, po measured after 3 hrs relative to control | Rattus norvegicus | 14 | organism-based format | Scientific Literature | ||
| 2. | ALA5031920 | B | Selectivity ratio of IC50 for P2X2 receptor (unknown origin) to IC50 for rat P2X3 receptor | 4 | assay format | Scientific Literature | |||
| 3. | ALA5031921 | B | Antagonist activity at P2X3 receptor (unknown origin) | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 4. | ALA5031922 | A | Oral bioavailability in rat at 1 mg/kg administered as cassette dose | Rattus norvegicus | 28 | organism-based format | Scientific Literature | ||
| 5. | ALA5031923 | A | Protein binding in rat plasma assessed as unbound fraction at 1 mg/kg administered as cassette dose | Rattus norvegicus | 28 | organism-based format | Scientific Literature | ||
| 6. | ALA5031924 | A | Free plasma concentration in rat plasma at 1 mg/kg administered as cassette dose | Rattus norvegicus | 28 | organism-based format | Scientific Literature | ||
| 7. | ALA5031925 | B | Antagonist activity at rat P2X3 receptor | Rattus norvegicus | 4 | single protein format | Scientific Literature | ||
| 8. | ALA5031926 | B | Antagonist activity at P2X1 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 9. | ALA5031927 | B | Antagonist activity at P2X2 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA5031928 | B | Antagonist activity at P2X4 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA5031929 | B | Antagonist activity at P2X7 receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 12. | ALA5031930 | P | Solubility of the compound in pH 1.2 JP1 fluid | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA5031931 | P | Solubility of the compound in JP2 fluid at pH 6.8 | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA5031932 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 15. | ALA5031933 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 16. | ALA5031934 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 17. | ALA5031935 | F | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 18. | ALA5031936 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 19. | ALA5031937 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 20. | ALA5031938 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 4 | organism-based format | Scientific Literature |
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