# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5031971 | ADME | Cytotoxicity against African green monkey COS-1 cell assessed as reduction in cell viability incubated for 24 hrs by by CellTiter 96 non-radioactive cell proliferation assay | Chlorocebus aethiops | 6 | ALA5030548 | cell-based format | Scientific Literature | |
2. | ALA5031972 | ADME | Drug uptake in cytoplasm of African green monkey COS-1 cells assessed as compound accumulation in cytoplasm at 20 uM incubated for 4 hrs in presence of FITC-labelled peptide by DAPI staining based inverted phase contrast fluorescence microscope analysis | Chlorocebus aethiops | 5 | ALA5030548 | subcellular format | Scientific Literature | |
3. | ALA5031973 | ADME | Drug uptake in nucleus of African green monkey COS-1 cells assessed as compound accumulation in nucleus at 20 uM incubated for 4 hrs in presence of FITC-labelled peptide by DAPI staining based inverted phase contrast fluorescence microscope analysis | Chlorocebus aethiops | 5 | ALA5030548 | subcellular format | Scientific Literature | |
4. | ALA5031978 | Binding | Inhibition of GRTH phosphorylation in mouse seminiferous tubule of testis assessed as reduction in pGRTH protein level at 100 uM measured after 16 hrs by western blot analysis | Mus musculus | 3 | ALA5030548 | tissue-based format | Scientific Literature | |
5. | ALA5031982 | Binding | Inhibition of GRTH phosphorylation (unknown origin) expressed in COS-1 cells assessed as reduction in pGRTH protein level at 5 to 100 uM measured after 16 hrs by western blot analysis | Homo sapiens | 3 | ALA5030548 | cell-based format | Scientific Literature | |
6. | ALA5031983 | ADME | Drug uptake in mouse seminiferous tubule of testis at 100 uM incubated for 16 hrs by immunofluorescence microscopic analysis | Mus musculus | 5 | ALA5030548 | tissue-based format | Scientific Literature |