| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5033503 | Binding | Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by fluorescence anisotropy assay | Homo sapiens | 3 | ALA5032516 | assay format | Scientific Literature | |
| 2. | ALA5033504 | Binding | Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli assessed as inhibition constant by fluorescence anisotropy assay | Homo sapiens | 2 | ALA5032516 | assay format | Scientific Literature | |
| 3. | ALA5033505 | Binding | Binding affinity to N-terminal His6-tagged human full length GRB2 SH2 domain (1 to 217 residues) expressed in Escherichia coli assessed as increase in protein thermal stability by measuring change in melting temperature by differential scanning fluorimetry | Homo sapiens | 2 | ALA5032516 | assay format | Scientific Literature | |
| 4. | ALA5033506 | ADME | Permeability of compound assessed as percentage transport at 500 uM after 5 hrs by PAMPA assay | 2 | ALA5032516 | assay format | Scientific Literature | ||
| 5. | ALA5033507 | ADME | Apparent permeability of compound at 500 uM after 5 hrs by PAMPA assay | 2 | ALA5032516 | assay format | Scientific Literature |
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