| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249913 | B | Protac activity at VHL/BRD3 (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 2. | ALA5249914 | B | Protac activity at VHL/BRD4 (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 3. | ALA5036172 | B | Protac activity at VHL/Brd4 in HEK293 cells assessed as Brd4 degradation after 4 hrs by Western blotting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA5036173 | B | Protac activity at VHL/Brd3 in HEK293 cells assessed as Brd3 degradation after 4 hrs by Western blotting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA5036174 | B | Protac activity at VHL/Brd2 in HEK293 cells assessed as Brd2 degradation after 4 hrs by Western blotting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA5036175 | F | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 24 hrs by Celltiter-Glo cell viability assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA5036176 | F | Antiproliferative activity against human 22Rv1 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo cell viability assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA5036177 | A | Permeability of the compound in PBS at pH 7.4 after 16 hrs by PAMPA | 8 | assay format | Scientific Literature | |||
| 9. | ALA5036178 | B | Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues)/BRD4 BD2 (333 to 460 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1alpha preincubated with Brd4 BD2 by ternary binding competitive fluorescence polarization assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 10. | ALA5036179 | B | Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1alpha by binary binding competitive fluorescence polarization assay | Homo sapiens | 8 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!