#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5030413	Binding	Displacement of [3H]-PGE2 from human EP3 receptor assessed as inhibition constant incubated for 2 hrs by TopCount scintillation counting method	Homo sapiens	27	ALA5029194	single protein format	Scientific Literature
2.	ALA5030414	Functional	Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated cAMP production incubated for 30 mins by TR-FRET assay	Homo sapiens	25	ALA5029194	cell-based format	Scientific Literature
3.	ALA5030415	Binding	Binding affinity to human EP1 receptor assessed as inhibition constant	Homo sapiens	1	ALA5029194	single protein format	Scientific Literature
4.	ALA5030416	Binding	Binding affinity to human EP2 receptor assessed as inhibition constant	Homo sapiens	1	ALA5029194	single protein format	Scientific Literature
5.	ALA5030417	Binding	Binding affinity to human EP4 receptor assessed as inhibition constant	Homo sapiens	1	ALA5029194	single protein format	Scientific Literature
6.	ALA5030418	Binding	Binding affinity to rat EP3 receptor assessed as inhibition constant	Rattus norvegicus	1	ALA5029194	single protein format	Scientific Literature
7.	ALA5030419	Functional	In vivo antagonist activity at ER3 receptor in Sprague-Dawley rat assessed as reversal of sulprostone induced reduction in circulating insulin levels at 10 times Ki, administered as iv infusion measured up to 30 mins after glucose administration by glucose tolerance test	Rattus norvegicus	1	ALA5029194	organism-based format	Scientific Literature
8.	ALA5030420	ADME	Free plasma concentration in Sprague-Dawley rat at 10 times Ki administered as iv infusion measured after 2 to 50 mins	Rattus norvegicus	1	ALA5029194	organism-based format	Scientific Literature
9.	ALA5030421	ADME	Cmax in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
10.	ALA5030423	ADME	AUClast in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	2	ALA5029194	organism-based format	Scientific Literature
11.	ALA5030425	ADME	Half life in Sprague-Dawley rat at 2 mg/kg, iv measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
12.	ALA5030426	ADME	Clearance in Sprague-Dawley rat at 2 mg/kg, iv measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
13.	ALA5030427	ADME	Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
14.	ALA5030428	ADME	Half life in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
15.	ALA5030429	ADME	AUC(0 to 24 hrs) in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature
16.	ALA5030430	ADME	Oral bioavailability in Sprague-Dawley rat at 10 mg/kg measured up to 24 hrs by LC-MS-MS analysis	Rattus norvegicus	6	ALA5029194	organism-based format	Scientific Literature