# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5044126 | A | Intrinsic clearance in Rhesus monkey at 0.1 mg/kg, iv by LC-MS/MS analysis | Macaca mulatta | 1 | ALA5042510 | organism-based format | Scientific Literature | |
2. | ALA5044128 | A | Unbound brain-to-plasma concentration ratio in rat at 2.5 uM incubated for 4 hrs by equilibrium dialysis method | Rattus norvegicus | 9 | ALA5042510 | cell-free format | Scientific Literature | |
3. | ALA5044131 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Sus scrofa | 16 | ALA5042510 | cell-based format | Scientific Literature | |
4. | ALA5044132 | A | Apparent permeability from apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Sus scrofa | 16 | ALA5042510 | cell-based format | Scientific Literature | |
5. | ALA5044133 | A | Intrinsic clearance in human hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Homo sapiens | 14 | ALA5042510 | cell-based format | Scientific Literature | |
6. | ALA5044134 | A | Intrinsic clearance in rat hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Rattus norvegicus | 14 | ALA5042510 | cell-based format | Scientific Literature | |
7. | ALA5044138 | A | Total plasma clearance in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA5042510 | organism-based format | Scientific Literature | |
8. | ALA5044139 | A | Intrinsic clearance in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA5042510 | organism-based format | Scientific Literature | |
9. | ALA5044140 | A | MRT in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA5042510 | organism-based format | Scientific Literature | |
10. | ALA5044141 | A | Intrinsic clearance in dog hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Canis lupus familiaris | 4 | ALA5042510 | cell-based format | Scientific Literature | |
11. | ALA5044143 | A | Total plasma clearance in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | ALA5042510 | organism-based format | Scientific Literature | |
12. | ALA5044145 | A | Intrinsic clearance in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | ALA5042510 | organism-based format | Scientific Literature | |
13. | ALA5044147 | A | MRT in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | ALA5042510 | organism-based format | Scientific Literature | |
14. | ALA5044148 | A | Oral bioavailability in Wistar Han rat at 10 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA5042510 | organism-based format | Scientific Literature | |
15. | ALA5044149 | A | Oral bioavailability in Beagle dog at 0.5 mg/kg by LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA5042510 | organism-based format | Scientific Literature | |
16. | ALA5044151 | A | Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral side in mouse Bcrp-transfected dog MDCK-II cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Canis lupus familiaris | 6 | ALA5042510 | cell-based format | Scientific Literature | |
17. | ALA5044152 | T | Inhibition of human ERG by voltage clamp assay | Homo sapiens | 11 | ALA5042510 | assay format | Scientific Literature | |
18. | ALA5044157 | T | Mutagenicity in Salmonella typhimurium TA1535 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | ALA5042510 | organism-based format | Scientific Literature | |
19. | ALA5044158 | T | Mutagenicity in Salmonella typhimurium TA98 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | ALA5042510 | organism-based format | Scientific Literature | |
20. | ALA5044159 | T | Mutagenicity in Salmonella typhimurium TA100 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | ALA5042510 | organism-based format | Scientific Literature |