| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5044126 | A | Intrinsic clearance in Rhesus monkey at 0.1 mg/kg, iv by LC-MS/MS analysis | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA5044128 | A | Unbound brain-to-plasma concentration ratio in rat at 2.5 uM incubated for 4 hrs by equilibrium dialysis method | Rattus norvegicus | 9 | cell-free format | Scientific Literature | ||
| 3. | ALA5044131 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Sus scrofa | 16 | cell-based format | Scientific Literature | ||
| 4. | ALA5044132 | A | Apparent permeability from apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Sus scrofa | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA5044133 | A | Intrinsic clearance in human hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 6. | ALA5044134 | A | Intrinsic clearance in rat hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA5044138 | A | Total plasma clearance in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 8. | ALA5044139 | A | Intrinsic clearance in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 9. | ALA5044140 | A | MRT in Wistar Han rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA5044141 | A | Intrinsic clearance in dog hepatocytes at 0.3 uM incubated for 90 mins by LC/MS/MS analysis | Canis lupus familiaris | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA5044143 | A | Total plasma clearance in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA5044145 | A | Intrinsic clearance in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA5044147 | A | MRT in Beagle dog at 0.25 mg/kg, iv by LC-MS/MS analysis | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA5044148 | A | Oral bioavailability in Wistar Han rat at 10 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA5044149 | A | Oral bioavailability in Beagle dog at 0.5 mg/kg by LC-MS/MS analysis | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA5044151 | A | Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral side in mouse Bcrp-transfected dog MDCK-II cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis | Canis lupus familiaris | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA5044152 | T | Inhibition of human ERG by voltage clamp assay | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 18. | ALA5044157 | T | Mutagenicity in Salmonella typhimurium TA1535 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA5044158 | T | Mutagenicity in Salmonella typhimurium TA98 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA5044159 | T | Mutagenicity in Salmonella typhimurium TA100 at 30 to 5000 ug incubated for 48 hrs in presence of liver S9 fraction by AMES test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature |
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