# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5051685 | F | Antiproliferative activity against human ES2 cells assessed as cell death after 72 hrs by Alamar blue viability assay | Homo sapiens | 14 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
2. | ALA5051686 | T | Hemolytic activity in human RBC measured by hemolysis assay | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
3. | ALA5051687 | F | Antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | 1 | ALA5050851 | organism-based format | Patent Bioactivity Data | |
4. | ALA5051688 | F | Antibacterial activity against Escherichia coli | Escherichia coli | 1 | ALA5050851 | organism-based format | Patent Bioactivity Data | |
5. | ALA5051689 | F | Antiproliferative activity against human ES2 cells at 10 uM assessed as time to induce 50% cell death measured by Annexin V/propidium iodide staining method | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
6. | ALA5051690 | F | Antiproliferative activity against human MIA PaCa-2 cells at 10 uM assessed as time to induce 50% cell death measured by Annexin V/propidium iodide staining method | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
7. | ALA5051691 | F | Antiproliferative activity against human HCT-116 cells at 10 uM assessed as time to induce 50% cell death measured by Annexin V/propidium iodide staining method | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
8. | ALA5051692 | F | Antiproliferative activity against human ES2 cells at 10 uM pretreated with 25 uM pan-caspase inhibitor Q-VD-OPh and assessed as induction of cell death measured after 13 hrs | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
9. | ALA5051693 | F | Antiproliferative activity against human HCT-116 cells at 10 uM pretreated with 25 uM pan-caspase inhibitor Q-VD-OPh and assessed as induction of cell death measured after 13 hrs | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
10. | ALA5051694 | F | Induction of PARP-1 cleavage in human ES2 cells measured after 1 to 7 hrs | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
11. | ALA5051695 | F | Induction of PARP-1 cleavage in human HCT-116 cells measured after 1 to 7 hrs | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
12. | ALA5051696 | F | Induction of apoptosis in human ES2 cells assessed as change in cell membrane blebbing | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
13. | ALA5051697 | F | Induction of apoptosis in human ES2 cells assessed as change in chromatin condensation | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
14. | ALA5051698 | F | Induction of ROS production in human ES2 cells at 5 to 25 uM measured by carboxy-H2DCFDA fluorescence assay | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
15. | ALA5051699 | F | Induction of ROS production in human HCT-116 cells at 5 to 25 uM measured by carboxy-H2DCFDA fluorescence assay | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
16. | ALA5051700 | F | Induction of ROS production in human ES2 cells at 10 to 25 uM measured by MitoSox red fluorescence assay | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
17. | ALA5051701 | F | Induction of ROS-induced lipid peroxidation in human ES2 cells at 10 uM measured after 1 hr | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
18. | ALA5051702 | F | Induction of ROS-induced lipid peroxidation in human HCT-116 cells at 10 uM measured after 1 hr | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
19. | ALA5051703 | F | Induction of ROS-induced lipid peroxidation in mouse 4T1 cells at 10 uM measured after 1 hr | Mus musculus | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data | |
20. | ALA5051704 | F | Induction of ROS-induced lipid peroxidation in human ES2 cells at 10 uM pretreated with DFO and measured after 1 hr | Homo sapiens | 1 | ALA5050851 | cell-based format | Patent Bioactivity Data |