# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5045598 | B | Inhibition of sigma 2 receptor (unknown origin) assessed as binding constant | Homo sapiens | 17 | single protein format | Scientific Literature | ||
2. | ALA5045600 | P | Aqueous solubility of the compound at pH 4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA5045601 | B | Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy 6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate addition and measured after 30 mins by BD FACSCalibur flow cytometry analysis | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
4. | ALA5045602 | P | Aqueous solubility of the compound at pH 7.4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA5045603 | P | Distribution coefficient, logD of compound at pH 7.4 by HPLC analysis | 33 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5045604 | B | Inhibition of fluorescent antagonist binding to mouse P2Y14R expressed in HEK293 cells preincubated for 30 mins followed by addition of 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy-6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate incubated for 30 mins by BD FACSCalibur flow cytometry analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
7. | ALA5045606 | B | Inhibition of sigma 1 receptor (unknown origin) assessed as binding constant | Homo sapiens | 8 | single protein format | Scientific Literature | ||
8. | ALA5045612 | B | Inhibition of adrenergic beta 3 receptor (unknown origin) assessed as binding constant | Homo sapiens | 5 | single protein format | Scientific Literature | ||
9. | ALA5045613 | B | Inhibition of adrenergic alpha 2B receptor (unknown origin) assessed as binding constant | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA5045648 | T | Antagonist activity at human ERG by patch clamp assay | Homo sapiens | 1 | assay format | Scientific Literature |