# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5049236 | Binding | Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluorimetric analysis | Homo sapiens | 6 | ALA5046287 | single protein format | Scientific Literature | |
2. | ALA5049237 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH1A1 at 10 uM in presence of NADH by fluorimetric analysis relative to hexanal | Homo sapiens | 5 | ALA5046287 | single protein format | Scientific Literature | |
3. | ALA5049242 | Binding | Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysis | Homo sapiens | 2 | ALA5046287 | single protein format | Scientific Literature | |
4. | ALA5049246 | Functional | Antiproliferative activity against human PC-3 cells expressing ALDH1A1 and ALDH3A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature | |
5. | ALA5049247 | Functional | Antiproliferative activity against human LNCaP cells expressing ALDH1A3 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature | |
6. | ALA5049248 | Functional | Antiproliferative activity against human DU145 cells expressing ALDH1A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature |