| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5038019 | B | Inhibition of recombinant human DDR1 (492 to end residues) using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 2. | ALA5038020 | F | Antiinflammatory activity against mouse primary bone marrow derived macrophages assessed as inhibition of LPS-induced IL-6 expression by ELISA | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 3. | ALA5038021 | F | Antiinflammatory activity against mouse primary bone marrow derived macrophages assessed as inhibition of LPS-induced IL-1beta expression at 10 uM by ELISA | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA5038022 | F | Antiinflammatory activity against mouse primary bone marrow derived macrophages assessed as inhibition of LPS-induced TNF expression at 10 uM by ELISA | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 5. | ALA5038023 | F | Antiinflammatory activity against human THP-1 derived macrophages assessed as inhibition of LPS-induced IL6 expression by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5038024 | F | Antiinflammatory activity against human THP-1 derived macrophage assessed as inhibition of LPS-induced IL-1beta expression at 10 uM by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5038025 | F | Antiinflammatory activity against human THP-1 derived macrophage assessed as inhibition of LPS-induced TNF expression at 10 uM by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5038026 | B | Inhibition of DDR1 in human THP-1 cells assessed as reduction in collagen induced DDR1 autophosphorylation by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA5038027 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as improvement in DSS induced weight loss at 5 to 10 mg/kg, po administered daily and measured after 5 to 8 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA5038028 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in fecal occult blood score at 5 to 10 mg/kg, po administered daily and measured after 9 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5038029 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as improvement in DSS reduced colon length at 5 to 10 mg/kg, po administered daily and measured after 9 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5038030 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in IL-6 transcription level in colon at 5 to 10 mg/kg, po administered daily by RT-qPCR analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5038031 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in IL-1beta transcription level in colon at 5 to 10 mg/kg, po administered daily by RT-qPCR analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA5038032 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in TNF transcription level in colon at 5 to 10 mg/kg, po administered daily by RT-qPCR analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5038033 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in serum IL-6 expression at 5 to 10 mg/kg, po administered daily by ELISA | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5038034 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in serum IL-1beta expression at 5 to 10 mg/kg, po administered daily by ELISA | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5038035 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in serum TNF expression at 5 to 10 mg/kg, po administered daily by ELISA | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5038036 | B | Inhibition of recombinant human DDR1 (492 to end residues) assessed as residual activity at 10 uM using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5038037 | B | Inhibition of recombinant human TRKC (510 to end residues) assessed as residual activity at 10 uM using GEEPLYWSFPAKKK as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA5038038 | F | Anti-colitis activity against DSS-induced IBD C57BL/6 mouse model assessed as reduction in inflammatory cell infiltration in colon at 5 to 10 mg/kg, po administered daily measured after 9 days by HE staining based analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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