# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5040386 | F | Inhibition of cell adhesion in human Neutrophils assessed as reduction on neutrophil at 1 to 100 uM incubated for 30 mins by DAPI staining based immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5040387 | P | Kinetic solubility of compound in PBS at pH 7.4 by UV-VIS absorption spectrophotometry analysis | 18 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA5040388 | P | Distribution coefficient, logD of compound at pH 7.4 by shake flask method based LC-MS/MS analysis | 24 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5040389 | A | Microsomal stability in human liver microsomes assessed as half life at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 22 | microsome format | Scientific Literature | ||
5. | ALA5040390 | A | Microsomal stability in mouse liver microsomes assessed as half life at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis | Mus musculus | 19 | microsome format | Scientific Literature | ||
6. | ALA5040391 | A | Microsomal stability in human liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 24 | microsome format | Scientific Literature | ||
7. | ALA5040392 | A | Microsomal stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis | Mus musculus | 23 | microsome format | Scientific Literature | ||
8. | ALA5040393 | F | Agonist activity at FPRL1 (unknown origin) expressed in CHO-K1 cells assessed as increase in calcium mobilization incubated for 2.5 hrs by cellular based FLIPR assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
9. | ALA5040394 | F | Agonist activity at FPRL1 (unknown origin) expressed in CHO-K1 cells assessed as stimulation of beta-arrestin recruitment incubated for 150 mins by beta-galactosidase based PathHunter assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
10. | ALA5040395 | F | Agonist activity at human FPR1 expressed in HEK293-A cells assessed as ERK phosphorylation level incubated for 5 mins by ELISA assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA5040396 | F | Agonist activity at human FPR2 expressed in HEK293-A cells assessed as ERK phosphorylation level incubated for 5 mins by ELISA assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA5040397 | A | Cmax in C57BL6 mouse at 10 mg/kg, ip measured upto 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA5040398 | A | Tmax in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA5040399 | A | Half life in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA5040400 | A | AUC (0 to t) in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA5040401 | A | AUC (0 to infinity) in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA5040402 | A | AUC extrapolated in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA5040403 | A | MRT(0 to t) in C57BL6 mouse at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA5040404 | F | Agonist activity at human FPR1 expressed in HEK293-A cells assessed as maximal ERK phosphorylation level at 30 uM incubated for 5 mins by ELISA assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA5040405 | F | Agonist activity at human FPR2 expressed in HEK293-A cells assessed as maximal ERK phosphorylation level at 30 uM incubated for 5 mins by ELISA assay | Homo sapiens | 2 | cell-based format | Scientific Literature |