#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5041938	Binding	Inhibition of JAK1/TYK2 in human H9 cells assessed as inhibition of IFNalpha-stimulated STAT1 phosphorylation at 5000 nM measured after 1 hr by Western blot analysis	Homo sapiens	1	ALA5038661	cell-based format	Scientific Literature
2.	ALA5041939	Binding	Inhibition of JAK1/JAK3 in human THP-1 cells assessed as inhibition of IL-4-stimulated STAT6 phosphorylation at 5000 nM measured after 1 hr by Western blot analysis	Homo sapiens	1	ALA5038661	cell-based format	Scientific Literature
3.	ALA5041940	Binding	Inhibition of human recombinant TYK2 (875 to end residues) using GGMEDIYFEFMGG as substrate incubated for 40 min in presence of ATP measured by scintillation counting based radiometry assay	Homo sapiens	1	ALA5038661	single protein format	Scientific Literature
4.	ALA5041941	Toxicity	Cytotoxicity against human LO2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	Homo sapiens	1	ALA5038661	cell-based format	Scientific Literature
5.	ALA5041942	Binding	Inhibition of JAK1 (unknown origin)	Homo sapiens	27	ALA5038661	single protein format	Scientific Literature
6.	ALA5041943	Binding	Inhibition of JAK2 (unknown origin)	Homo sapiens	27	ALA5038661	single protein format	Scientific Literature
7.	ALA5041944	Binding	Inhibition of JAK3 (unknown origin)	Homo sapiens	26	ALA5038661	single protein format	Scientific Literature
8.	ALA5041945	Binding	Inhibition of TYK2 (unknown origin)	Homo sapiens	27	ALA5038661	single protein format	Scientific Literature
9.	ALA5041946	ADME	Metabolic stability in human liver microsomes	Homo sapiens	3	ALA5038661	microsome format	Scientific Literature
10.	ALA5041947	ADME	Cmax in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	2	ALA5038661	organism-based format	Scientific Literature
11.	ALA5041948	ADME	Clearance in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	2	ALA5038661	organism-based format	Scientific Literature
12.	ALA5041949	ADME	Half life in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	2	ALA5038661	organism-based format	Scientific Literature
13.	ALA5041950	ADME	AUC (0 to 24 hrs) in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	2	ALA5038661	organism-based format	Scientific Literature
14.	ALA5041951	ADME	Oral bioavailability in Sprague-Dawley rat at 5 mg/kg measured upto 24 hrs by LC-MS/MS analysis	Rattus norvegicus	2	ALA5038661	organism-based format	Scientific Literature
15.	ALA5041952	Binding	Inhibition of human recombinant full length Aurora-A using LRRASLG as substrate incubated for 40 min measured by scintillation counting based radiometry assay	Homo sapiens	1	ALA5038661	single protein format	Scientific Literature
16.	ALA5041953	Binding	Inhibition of human recombinant JAK1 (866 to end residues) using GEEPLYWSFPAKK as substrate incubated for 40 min in presence of ATP measured by scintillation counting based radiometry assay	Homo sapiens	1	ALA5038661	single protein format	Scientific Literature
17.	ALA5041954	Binding	Inhibition of human recombinant JAK2 (808 to end residues) using KTFCGTPEYLAPE as substrate incubated for 40 min in presence of ATP measured by scintillation counting based radiometry assay	Homo sapiens	1	ALA5038661	single protein format	Scientific Literature
18.	ALA5041955	Binding	Inhibition of human recombinant JAK3 (781 to end residues) using GGEEEEYFELVKK as substrate incubated for 40 min in presence of ATP measured by scintillation counting based radiometry assay	Homo sapiens	1	ALA5038661	single protein format	Scientific Literature
19.	ALA5041956	Binding	Inhibition of JAK2 in human TF-1 cells assessed as inhibition of GM-CSF-stimulated STAT5 phosphorylation at 5000 nM measured after 1 hr by Western blot analysis	Homo sapiens	1	ALA5038661	cell-based format	Scientific Literature
20.	ALA5041957	Binding	Inhibition of JAK1/JAK2/TYK2 in human TF-1 cells assessed as inhibition of rhIL-6-stimulated STAT3 phosphorylation at 5000 nM measured after 1.5 hrs by Western blot analysis	Homo sapiens	1	ALA5038661	cell-based format	Scientific Literature