# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5050624 | B | Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 60 mins by Kinase-GLO reagent based assay | Homo sapiens | 25 | ALA5046317 | single protein format | Scientific Literature | |
2. | ALA5050625 | F | Antiproliferative activity against human MOG-G-UVW cells assessed as inhibition of cell proliferation incubated for 72 hrs by cell titer-Glo assay | Homo sapiens | 25 | ALA5046317 | cell-based format | Scientific Literature | |
3. | ALA5050626 | A | Substrate activity at P-gp (unknown origin) transfected in rat MDCK-MDR1 expressing Mdr1 gene assessed as efflux ratio of permeability across basolateral to apical membrane at 0.1 uM | Homo sapiens | 1 | ALA5046317 | cell-based format | Scientific Literature | |
4. | ALA5050627 | A | Drug metabolism in rat liver microsomes assessed as GSH-adduct formation at 1 mg/ml and measured after 60 mins in presence of glutathione and NADPH by ion chromatogram analysis relative to control | Rattus norvegicus | 24 | ALA5046317 | microsome format | Scientific Literature |