# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5045597 | P | Stability of the compound in aqueous medium at pH 7.4 assessed as half life in presence of porcine liver esterase | 5 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA5045598 | B | Inhibition of sigma 2 receptor (unknown origin) assessed as binding constant | Homo sapiens | 17 | single protein format | Scientific Literature | ||
3. | ALA5045603 | P | Distribution coefficient, logD of compound at pH 7.4 by HPLC analysis | 33 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5045610 | B | Inhibition of serotonin 5HT1D receptor (unknown origin) assessed as binding constant | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA5045611 | B | Inhibition of serotonin 5HT2C receptor (unknown origin) assessed as binding constant | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA5045636 | A | Prodrug conversion in aqueous medium at pH 7.4 assessed as conversion of 4-(4-((1S,4S,5S)-2-(Ethoxycarbonyl)-2-azabicyclo[2.2.1]heptan-5-yl)phenyl)-7-(4-(trifluoro-methyl)phenyl)-2-naphthoic acid at 72 hrs by HPLC analysis | 2 | assay format | Scientific Literature | |||
7. | ALA5045643 | F | Antiinflammatory activity in C57BL/6J mouse model of ovalbumin/Aspergillus-induced allergic asthma assessed as reduction in recruitment of neutrophils into airway at 10 mg/kg, ip administered 30 mins prior to allergen challenge and measured after 16 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA5045644 | F | Antiinflammatory activity in C57BL/6J mouse model of ovalbumin/Aspergillus-induced allergic asthma assessed as reduction in recruitment of eosinophils into airway at 10 mg/kg, ip administered 30 mins prior to allergen challenge and measured after 16 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA5045645 | F | Antiinflammatory activity in C57BL/6J mouse model of ovalbumin/Aspergillus-induced allergic asthma assessed as reduction in recruitment of lymphocytes into airway at 10 mg/kg, ip administered 30 mins prior to allergen challenge and measured after 16 days | Mus musculus | 1 | organism-based format | Scientific Literature |