# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5043862 | A | Protein binding to human plasma at 0.7 nmol for 40 mins by radiometric ultrafiltration assay relative to control | Homo sapiens | 4 | ALA5042503 | cell-free format | Scientific Literature | |
2. | ALA5043863 | A | Protein binding in human serum albumin at 45 uM for 40 mins by radiometric ultrafiltration assay relative to control | Homo sapiens | 4 | ALA5042503 | single protein format | Scientific Literature | |
3. | ALA5043864 | P | Lipophilicity, logD of compound at pH 7.4 under shaking condition by HPLC analysis | 10 | ALA5042503 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5043865 | B | Binding affinity to human serum albumin assessed as dissociation constant radiometric ultrafiltration assay | Homo sapiens | 8 | ALA5042503 | single protein format | Scientific Literature | |
5. | ALA5043866 | B | Binding affinity to mouse SST2 expressed in mouse pheochromocytoma cells assessed as dissociation constant for 1 hr by nanodrop spectrophotometric analysis | Mus musculus | 8 | ALA5042503 | cell-based format | Scientific Literature | |
6. | ALA5043867 | B | Binding affinity to mouse SST2 expressed in mouse pheochromocytoma cells assessed as maximum binding capacity for 1 hr by Nanodrop spectrophotometric analysis | Mus musculus | 8 | ALA5042503 | cell-based format | Scientific Literature | |
7. | ALA5043868 | A | Stability in mouse plasma assessed as half life in presence of BNPP measured upto 24 hrs by radio-HPLC analysis | Mus musculus | 8 | ALA5042503 | cell-free format | Scientific Literature | |
8. | ALA5043869 | A | Stability in human plasma assessed as half life in presence of BNPP measured upto 24 hrs by radio-HPLC analysis | Homo sapiens | 8 | ALA5042503 | cell-free format | Scientific Literature | |
9. | ALA5043870 | A | Drug uptake in mouse pheochromocytoma cells assessed as total bound radioligand per mg protein in pH 7.4 PBS buffer at 2 nM measured after 1 hr by nanodrop spectrophotometric analysis | Mus musculus | 3 | ALA5042503 | cell-based format | Scientific Literature | |
10. | ALA5043871 | A | Drug accumulation in MPC cells allografted Rj:NMRI-Foxn1 nu/nu mouse assessed as SST2 specific accumulation in MPC tumor at 7 to 10 MBq, iv and measured upto 48 hrs by positron emission tomography | Mus musculus | 3 | ALA5042503 | organism-based format | Scientific Literature | |
11. | ALA5043872 | A | Drug accumulation in MPC cells allografted Rj:NMRI-Foxn1 nu/nu mouse assessed as SST2 specific accumulation in MPC tumor at 7 to 10 MBq, iv and measured at 48 hrs by positron emission tomography | Mus musculus | 2 | ALA5042503 | organism-based format | Scientific Literature | |
12. | ALA5043873 | A | Drug uptake in mouse pheochromocytoma cells assessed as total bound radioligand per mg protein in pH 2.8 glycine buffer at 2 nM measured after 1 hr by nanodrop spectrophotometric analysis | Mus musculus | 3 | ALA5042503 | cell-based format | Scientific Literature | |
13. | ALA5043875 | A | Drug accumulation in MPC cells allografted Rj:NMRI-Foxn1 nu/nu mouse assessed as SST2 specific accumulation in MPC tumor at 7 to 10 MBq, iv and measured at 24 hrs by positron emission tomography | Mus musculus | 2 | ALA5042503 | organism-based format | Scientific Literature | |
14. | ALA5043881 | A | Drug accumulation in MPC cells allografted Rj:NMRI-Foxn1 nu/nu mouse assessed as SST2 specific accumulation in heart at 7 to 10 MBq, iv and measured at 24 hrs by positron emission tomography | Mus musculus | 2 | ALA5042503 | organism-based format | Scientific Literature |