| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5046080 | B | Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual luciferase reporter gene based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA5046081 | B | Inhibition of GDF-11 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual luciferase reporter gene based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA5046082 | B | Inhibition of activin A (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA5046083 | B | Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5046084 | A | Stability of the compound assessed as bovine pancreas trypsin-mediated parent compound depletion incubated for 400 mins by RP-HPLC analysis | Bos taurus | 2 | assay format | Scientific Literature | ||
| 6. | ALA5046085 | A | Stability of the compound assessed as bovine pancreas alphachymotrypsin-mediated parent compound depletion incubated for 400 mins by RP-HPLC analysis | Bos taurus | 2 | assay format | Scientific Literature | ||
| 7. | ALA5046086 | F | Invivo inhibition of myostatin in C57BL/6J mouse assessed as increase in weight of tibialis anterior muscles normalized with body weight at 0.75 mM, IM administered for 28 days | Mus musculus | 2 | assay format | Scientific Literature | ||
| 8. | ALA5046087 | F | Invivo inhibition of myostatin in C57BL/6J mouse assessed as increase in weight of tibialis anterior muscles at 0.75 mM, IM administered for 28 days relative to control | Mus musculus | 2 | assay format | Scientific Literature | ||
| 9. | ALA5233119 | B | Photo-oxygenation mediated inactivation of human recombinant Myostatin expressed in Escherichia coli cells photoirradiated for 30 mins using LED followed by incubation with luciferase reporter transfected HEK293 cells for 4 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!